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Progestin and AdipoQ Receptor 3 Upregulates Fibronectin and Intercellular Adhesion Molecule-1 in Glomerular Mesangial Cells via Activating NF-κB Signaling Pathway Under High Glucose Conditions
BACKGROUND: Progestin and adipoQ receptor 3 (PAQR3), is a Golgi-anchored membrane protein containing seven transmembrane helices. It has been demonstrated that PAQR3 mediates insulin resistance, glucose and lipid metabolism, and inflammation. In addition, kidney inflammatory fibrosis is an important...
Autores principales: | Zou, Yezi, Chen, Zhiquan, Li, Jie, Gong, Wenyan, Zhang, Lei, Xu, Futian, Chen, Lihao, Liu, Peiqing, Huang, Heqing |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5999916/ https://www.ncbi.nlm.nih.gov/pubmed/29930535 http://dx.doi.org/10.3389/fendo.2018.00275 |
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