CT/MRI影像融合对肺癌脑转移放射治疗靶区勾画的影响

BACKGROUND AND OBJECTIVE: Accurate target delineation in radiation therapy is a key component of the treatment regimen for brain metastasis for which CT/MRI fusion technology provides a feasible method. The aim of this study is to explore the role of CT/MRI image registration in target delineation for lung cancer with brain metastasis. METHODS: The image data of 31 patients were processed using Oncentra MasterPlan. The GTVs were delineated on CT and CT/MRI images, and their differences were compared to analyze the impact of the maximum average error and tumor edema on target delineation. RESULTS: The GTVs delineated on CT/MRI images were markedly smaller than those delineated on CT images. Target delineation was clearly influenced by edema. CONCLUSION: The technology of CT/MRI image registration can improve the accuracy of target delineation for lung cancer with brain metastasis.