Magnolin promotes autophagy and cell cycle arrest via blocking LIF/Stat3/Mcl-1 axis in human colorectal cancers

Magnolin is a multi-bioactive natural compound that possesses underlying anti-cancer properties. However, the mechanisms underlying remain to be elucidated. Here, we report the role of magnolin in suppressing human colorectal cancer (CRC) cells via activating autophagy and cell cycle arrest in vitro...

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Detalles Bibliográficos
Autores principales: Yu, Haiyang, Yin, Shuangshuang, Zhou, Shiyue, Shao, Yingying, Sun, Jiachen, Pang, Xu, Han, Lifeng, Zhang, Yi, Gao, Xiumei, Jin, Chengyun, Qiu, Yuling, Wang, Tao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5999973/
https://www.ncbi.nlm.nih.gov/pubmed/29899555
http://dx.doi.org/10.1038/s41419-018-0660-4

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