Downregulation of HS6ST2 by miR-23b-3p enhances matrix degradation through p38 MAPK pathway in osteoarthritis

Osteoarthritis (OA) is the most common form of arthritis involving major structural changes of peripheral joints and local or systemic inflammation and in lack of therapeutic approaches because of complexity of underlying molecular basis. Our previous work showed that HS6ST2, an enzyme involved in t...

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Detalles Bibliográficos
Autores principales: Guo, Yuanxu, Min, Zixin, Jiang, Congshan, Wang, Wei, Yan, Jidong, Xu, Peng, Xu, Ke, Xu, Jing, Sun, Mengyao, Zhao, Yitong, Hussain, Safdar, Zhang, Rui, Wang, Quancheng, Han, Yan, Zhang, Fujun, Zhu, Wenhua, Li, Dongmin, Meng, Liesu, Sun, Jian, Lu, Shemin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5999974/
https://www.ncbi.nlm.nih.gov/pubmed/29899528
http://dx.doi.org/10.1038/s41419-018-0729-0

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