Jnk2 deficiency increases the rate of glaucomatous neurodegeneration in ocular hypertensive DBA/2J mice

The cJun N-terminal kinases (JNKs; JNK1, JNK2, and JNK3) promote degenerative processes after neuronal injury and in disease. JNK2 and JNK3 have been shown to promote retinal ganglion cell (RGC) death after optic nerve injury. In their absence, long-term survival of RGC somas is significantly increa...

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Detalles Bibliográficos
Autores principales: Harder, Jeffrey M., Williams, Pete A., Soto, Ileana, Foxworth, Nicole E., Fernandes, Kimberly A., Freeburg, Nelson F., Libby, Richard T., John, Simon. W. M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6000001/
https://www.ncbi.nlm.nih.gov/pubmed/29899326
http://dx.doi.org/10.1038/s41419-018-0705-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6000001/
https://www.ncbi.nlm.nih.gov/pubmed/29899326
http://dx.doi.org/10.1038/s41419-018-0705-8

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