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瘦素系统与非小细胞肺癌关系的研究进展
Leptin system plays an important role in lung inflammation and tumorigenesis, but the precise function in the tumormicrovironment and the prognosis value of the leptin system in lung cancer have not been fully elucidated. This review will focus on the relationship between leptin system and non-small...
| Formato: | Online Artículo Texto |
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| Lenguaje: | English |
| Publicado: |
中国肺癌杂志编辑部
2014
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6000024/ https://www.ncbi.nlm.nih.gov/pubmed/24758911 http://dx.doi.org/10.3779/j.issn.1009-3419.2014.04.10 |
| _version_ | 1783331593403760640 |
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| collection | PubMed |
| description | Leptin system plays an important role in lung inflammation and tumorigenesis, but the precise function in the tumormicrovironment and the prognosis value of the leptin system in lung cancer have not been fully elucidated. This review will focus on the relationship between leptin system and non-small cell lung cancer (NSCLC), in which special attentions will be paid on the expression of leption and its receptor (LepR) in peripheral blood and tumor tissues, leptin-related signal transduction pathways, the interaction between leption and regulatory T cells (Treg) and the gene polymorphisms of leptin and leptin receptor, and possibly provide new strategies for diagnosis and treatment of NSCLC. |
| format | Online Article Text |
| id | pubmed-6000024 |
| institution | National Center for Biotechnology Information |
| language | English |
| publishDate | 2014 |
| publisher | 中国肺癌杂志编辑部 |
| record_format | MEDLINE/PubMed |
| spelling | pubmed-60000242018-07-06 瘦素系统与非小细胞肺癌关系的研究进展 Zhongguo Fei Ai Za Zhi 综述 Leptin system plays an important role in lung inflammation and tumorigenesis, but the precise function in the tumormicrovironment and the prognosis value of the leptin system in lung cancer have not been fully elucidated. This review will focus on the relationship between leptin system and non-small cell lung cancer (NSCLC), in which special attentions will be paid on the expression of leption and its receptor (LepR) in peripheral blood and tumor tissues, leptin-related signal transduction pathways, the interaction between leption and regulatory T cells (Treg) and the gene polymorphisms of leptin and leptin receptor, and possibly provide new strategies for diagnosis and treatment of NSCLC. 中国肺癌杂志编辑部 2014-04-20 /pmc/articles/PMC6000024/ /pubmed/24758911 http://dx.doi.org/10.3779/j.issn.1009-3419.2014.04.10 Text en 版权所有©《中国肺癌杂志》编辑部2014 https://creativecommons.org/licenses/by/3.0/ This is an open access article distributed in accordance with the terms of the Creative Commons Attribution (CC BY 3.0) License. See: https://creativecommons.org/licenses/by/3.0/ |
| spellingShingle | 综述 瘦素系统与非小细胞肺癌关系的研究进展 |
| title | 瘦素系统与非小细胞肺癌关系的研究进展 |
| title_full | 瘦素系统与非小细胞肺癌关系的研究进展 |
| title_fullStr | 瘦素系统与非小细胞肺癌关系的研究进展 |
| title_full_unstemmed | 瘦素系统与非小细胞肺癌关系的研究进展 |
| title_short | 瘦素系统与非小细胞肺癌关系的研究进展 |
| title_sort | 瘦素系统与非小细胞肺癌关系的研究进展 |
| topic | 综述 |
| url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6000024/ https://www.ncbi.nlm.nih.gov/pubmed/24758911 http://dx.doi.org/10.3779/j.issn.1009-3419.2014.04.10 |
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