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A rare case of primary spinal cord melanoma

Primary central nervous system melanoma is rare, accounting for approximately 1% of total melanoma cases (1-3). Primary central nervous system melanoma localized to the spinal cord is even rarer. The cervical and thoracic levels are most frequently involved. There are no pathognomonic imaging charac...

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Autores principales: Wuerdeman, Marc, Douglass, Samuel, Abda, Rafik Ben, Krasnokutsky, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6000063/
https://www.ncbi.nlm.nih.gov/pubmed/29904488
http://dx.doi.org/10.1016/j.radcr.2018.01.009
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author Wuerdeman, Marc
Douglass, Samuel
Abda, Rafik Ben
Krasnokutsky, Michael
author_facet Wuerdeman, Marc
Douglass, Samuel
Abda, Rafik Ben
Krasnokutsky, Michael
author_sort Wuerdeman, Marc
collection PubMed
description Primary central nervous system melanoma is rare, accounting for approximately 1% of total melanoma cases (1-3). Primary central nervous system melanoma localized to the spinal cord is even rarer. The cervical and thoracic levels are most frequently involved. There are no pathognomonic imaging characteristics and diagnosis must be confirmed immunohistologically. The preferred treatment is gross total resection. Utilization of adjuvant radiotherapy and chemotherapy may improve disease-free survival. The prognosis for primary central nervous system melanoma is generally better than that of metastatic and cutaneous melanoma, although there are relatively few cases from which to draw conclusions. We report a case of a 64-year-old woman diagnosed with primary spinal melanoma of the thoracic spine treated with subtotal surgical resection followed by adjuvant radiation therapy.
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spelling pubmed-60000632018-06-14 A rare case of primary spinal cord melanoma Wuerdeman, Marc Douglass, Samuel Abda, Rafik Ben Krasnokutsky, Michael Radiol Case Rep Spine Primary central nervous system melanoma is rare, accounting for approximately 1% of total melanoma cases (1-3). Primary central nervous system melanoma localized to the spinal cord is even rarer. The cervical and thoracic levels are most frequently involved. There are no pathognomonic imaging characteristics and diagnosis must be confirmed immunohistologically. The preferred treatment is gross total resection. Utilization of adjuvant radiotherapy and chemotherapy may improve disease-free survival. The prognosis for primary central nervous system melanoma is generally better than that of metastatic and cutaneous melanoma, although there are relatively few cases from which to draw conclusions. We report a case of a 64-year-old woman diagnosed with primary spinal melanoma of the thoracic spine treated with subtotal surgical resection followed by adjuvant radiation therapy. Elsevier 2018-02-20 /pmc/articles/PMC6000063/ /pubmed/29904488 http://dx.doi.org/10.1016/j.radcr.2018.01.009 Text en http://creativecommons.org/licenses/by-nc-nd/4.0/ This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Spine
Wuerdeman, Marc
Douglass, Samuel
Abda, Rafik Ben
Krasnokutsky, Michael
A rare case of primary spinal cord melanoma
title A rare case of primary spinal cord melanoma
title_full A rare case of primary spinal cord melanoma
title_fullStr A rare case of primary spinal cord melanoma
title_full_unstemmed A rare case of primary spinal cord melanoma
title_short A rare case of primary spinal cord melanoma
title_sort rare case of primary spinal cord melanoma
topic Spine
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6000063/
https://www.ncbi.nlm.nih.gov/pubmed/29904488
http://dx.doi.org/10.1016/j.radcr.2018.01.009
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