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Development of specific nanobodies (VHH) for CD19 immuno-targeting of human B-lymphocytes

OBJECTIVE(S): CD19 is a transmembrane glycoprotein of immunoglobulin superfamily. In order to treat lymphoma, monoclonal antibodies (mAb) can target different antigens, including CD19, CD20 and CD22 on the surface of B-cells. Along with biotechnology progress, a new generation of antibodies is intro...

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Detalles Bibliográficos
Autores principales: Banihashemi, Seyed Reza, Hosseini, Ahmad Zavaran, Rahbarizadeh, Fatemeh, Ahmadvand, Davoud
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Mashhad University of Medical Sciences 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6000210/
https://www.ncbi.nlm.nih.gov/pubmed/29922424
http://dx.doi.org/10.22038/IJBMS.2018.26778.6557