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肺腺癌驱动基因研究相关进展
The adenocarcinoma of the lung has recently shown peculiar molecular characteristics, which relate with both carcinogenesis and response to targeted drugs. Several molecular alterations have been defined as "driver oncogenes" responsible for both the initiation and maintenance of the malig...
| Formato: | Online Artículo Texto |
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| Lenguaje: | English |
| Publicado: |
中国肺癌杂志编辑部
2013
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6000391/ https://www.ncbi.nlm.nih.gov/pubmed/23425901 http://dx.doi.org/10.3779/j.issn.1009-3419.2013.02.06 |
| _version_ | 1783331708848832512 |
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| collection | PubMed |
| description | The adenocarcinoma of the lung has recently shown peculiar molecular characteristics, which relate with both carcinogenesis and response to targeted drugs. Several molecular alterations have been defined as "driver oncogenes" responsible for both the initiation and maintenance of the malignancy. So far, 50% of lung adenocarcinoma has been found harbouring driver oncogenes, in which epidermal growth factor receptor pathway plays important roles. In this review, we will report mainly the advances on significance of some latest driver mutations. |
| format | Online Article Text |
| id | pubmed-6000391 |
| institution | National Center for Biotechnology Information |
| language | English |
| publishDate | 2013 |
| publisher | 中国肺癌杂志编辑部 |
| record_format | MEDLINE/PubMed |
| spelling | pubmed-60003912018-07-06 肺腺癌驱动基因研究相关进展 Zhongguo Fei Ai Za Zhi 综述 The adenocarcinoma of the lung has recently shown peculiar molecular characteristics, which relate with both carcinogenesis and response to targeted drugs. Several molecular alterations have been defined as "driver oncogenes" responsible for both the initiation and maintenance of the malignancy. So far, 50% of lung adenocarcinoma has been found harbouring driver oncogenes, in which epidermal growth factor receptor pathway plays important roles. In this review, we will report mainly the advances on significance of some latest driver mutations. 中国肺癌杂志编辑部 2013-02-20 /pmc/articles/PMC6000391/ /pubmed/23425901 http://dx.doi.org/10.3779/j.issn.1009-3419.2013.02.06 Text en 版权所有©《中国肺癌杂志》编辑部2013 https://creativecommons.org/licenses/by/3.0/ This is an open access article distributed in accordance with the terms of the Creative Commons Attribution (CC BY 3.0) License. See: https://creativecommons.org/licenses/by/3.0/ |
| spellingShingle | 综述 肺腺癌驱动基因研究相关进展 |
| title | 肺腺癌驱动基因研究相关进展 |
| title_full | 肺腺癌驱动基因研究相关进展 |
| title_fullStr | 肺腺癌驱动基因研究相关进展 |
| title_full_unstemmed | 肺腺癌驱动基因研究相关进展 |
| title_short | 肺腺癌驱动基因研究相关进展 |
| title_sort | 肺腺癌驱动基因研究相关进展 |
| topic | 综述 |
| url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6000391/ https://www.ncbi.nlm.nih.gov/pubmed/23425901 http://dx.doi.org/10.3779/j.issn.1009-3419.2013.02.06 |
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