非小细胞肺癌驱动基因突变及靶向治疗的研究进展

Lung cancer is the leading cause of cancer-related mortality in the worldwide. The discovery of drive gene makes tumor treatment is no longer "one-size-fits-all". Targeted therapy to change the present situation of cancer drugs become "bullet" with eyes, the effect is visible and...

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Detalles Bibliográficos
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 中国肺癌杂志编辑部 2014
Materias:
综述
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6000403/
https://www.ncbi.nlm.nih.gov/pubmed/25342042
http://dx.doi.org/10.3779/j.issn.1009-3419.2014.10.07
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description Lung cancer is the leading cause of cancer-related mortality in the worldwide. The discovery of drive gene makes tumor treatment is no longer "one-size-fits-all". Targeted therapy to change the present situation of cancer drugs become "bullet" with eyes, the effect is visible and bring a revolution in the treatment of lung cancer. The diver gene and targeted therapy have became the new cedule of non-small cell lung cancer (NSCLC). Society of Clinical Oncology (ASCO) has showed 11 kinds of diver genes. Here, we review the functional and structural characteristics and the targeted therapy in the 11 kinds of driver gene mutations.
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spelling pubmed-60004032018-07-06 非小细胞肺癌驱动基因突变及靶向治疗的研究进展 Zhongguo Fei Ai Za Zhi 综述 Lung cancer is the leading cause of cancer-related mortality in the worldwide. The discovery of drive gene makes tumor treatment is no longer "one-size-fits-all". Targeted therapy to change the present situation of cancer drugs become "bullet" with eyes, the effect is visible and bring a revolution in the treatment of lung cancer. The diver gene and targeted therapy have became the new cedule of non-small cell lung cancer (NSCLC). Society of Clinical Oncology (ASCO) has showed 11 kinds of diver genes. Here, we review the functional and structural characteristics and the targeted therapy in the 11 kinds of driver gene mutations. 中国肺癌杂志编辑部 2014-10-20 /pmc/articles/PMC6000403/ /pubmed/25342042 http://dx.doi.org/10.3779/j.issn.1009-3419.2014.10.07 Text en 版权所有©《中国肺癌杂志》编辑部2014 https://creativecommons.org/licenses/by/3.0/ This is an open access article distributed in accordance with the terms of the Creative Commons Attribution (CC BY 3.0) License. See: https://creativecommons.org/licenses/by/3.0/
spellingShingle 综述
非小细胞肺癌驱动基因突变及靶向治疗的研究进展
title 非小细胞肺癌驱动基因突变及靶向治疗的研究进展
title_full 非小细胞肺癌驱动基因突变及靶向治疗的研究进展
title_fullStr 非小细胞肺癌驱动基因突变及靶向治疗的研究进展
title_full_unstemmed 非小细胞肺癌驱动基因突变及靶向治疗的研究进展
title_short 非小细胞肺癌驱动基因突变及靶向治疗的研究进展
title_sort 非小细胞肺癌驱动基因突变及靶向治疗的研究进展
topic 综述
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6000403/
https://www.ncbi.nlm.nih.gov/pubmed/25342042
http://dx.doi.org/10.3779/j.issn.1009-3419.2014.10.07

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