mTOR在肺类癌中的研究进展

Mammalian target of rapamycin (mTOR), a main protein kinase in the phosphoinositide 3-kinase (PI3K)/AKT/mTOR signaling pathway, is an important intracellular mediator involved in multiple celluar functions including proliferation, differentiation, apoptosis, tumorigenesis, and angiogenesis. Recently...

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Detalles Bibliográficos
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 中国肺癌杂志编辑部 2013
Materias:
综述
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6000455/
https://www.ncbi.nlm.nih.gov/pubmed/23327873
http://dx.doi.org/10.3779/j.issn.1009-3419.2013.01.08
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collection PubMed
description Mammalian target of rapamycin (mTOR), a main protein kinase in the phosphoinositide 3-kinase (PI3K)/AKT/mTOR signaling pathway, is an important intracellular mediator involved in multiple celluar functions including proliferation, differentiation, apoptosis, tumorigenesis, and angiogenesis. Recently, the high expression of mTOR and mTOR-related kinase have been found in neuroendocrin tumors. Therefore, mTOR pathway represents an attractive target for new anticancer therapies except surgery.
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spelling pubmed-60004552018-07-06 mTOR在肺类癌中的研究进展 Zhongguo Fei Ai Za Zhi 综述 Mammalian target of rapamycin (mTOR), a main protein kinase in the phosphoinositide 3-kinase (PI3K)/AKT/mTOR signaling pathway, is an important intracellular mediator involved in multiple celluar functions including proliferation, differentiation, apoptosis, tumorigenesis, and angiogenesis. Recently, the high expression of mTOR and mTOR-related kinase have been found in neuroendocrin tumors. Therefore, mTOR pathway represents an attractive target for new anticancer therapies except surgery. 中国肺癌杂志编辑部 2013-01-20 /pmc/articles/PMC6000455/ /pubmed/23327873 http://dx.doi.org/10.3779/j.issn.1009-3419.2013.01.08 Text en 版权所有©《中国肺癌杂志》编辑部2013 https://creativecommons.org/licenses/by/3.0/ This is an open access article distributed in accordance with the terms of the Creative Commons Attribution (CC BY 3.0) License. See: https://creativecommons.org/licenses/by/3.0/
spellingShingle 综述
mTOR在肺类癌中的研究进展
title mTOR在肺类癌中的研究进展
title_full mTOR在肺类癌中的研究进展
title_fullStr mTOR在肺类癌中的研究进展
title_full_unstemmed mTOR在肺类癌中的研究进展
title_short mTOR在肺类癌中的研究进展
title_sort mtor在肺类癌中的研究进展
topic 综述
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6000455/
https://www.ncbi.nlm.nih.gov/pubmed/23327873
http://dx.doi.org/10.3779/j.issn.1009-3419.2013.01.08

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