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非小细胞肺癌中EMT的发生机制及预后价值的研究进展
Epithelial to mesenchymal transition (EMT) has an important role in the development of embryo, as well as that in the metastasis of non-small cell lung cancer (NSCLC). Recent researches have demonstrated that both morphological and phenotypic conversions emerge in cells undergoing EMT. As most of re...
Formato: | Online Artículo Texto |
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Lenguaje: | English |
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中国肺癌杂志编辑部
2014
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6000464/ https://www.ncbi.nlm.nih.gov/pubmed/25034589 http://dx.doi.org/10.3779/j.issn.1009-3419.2014.07.13 |
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collection | PubMed |
description | Epithelial to mesenchymal transition (EMT) has an important role in the development of embryo, as well as that in the metastasis of non-small cell lung cancer (NSCLC). Recent researches have demonstrated that both morphological and phenotypic conversions emerge in cells undergoing EMT. As most of relevant studies were on other cancers, it is essential to uncover whether it is the similar mechanisms accounting for EMT in NSCLC. With the progress of the studies, EMT-related basic researches are gradually applied to predicting the prognosis of NSCLC. The aim of this article was to discuss the mechanisms related to EMT emerging in NSCLC. |
format | Online Article Text |
id | pubmed-6000464 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2014 |
publisher | 中国肺癌杂志编辑部 |
record_format | MEDLINE/PubMed |
spelling | pubmed-60004642018-07-06 非小细胞肺癌中EMT的发生机制及预后价值的研究进展 Zhongguo Fei Ai Za Zhi 综述 Epithelial to mesenchymal transition (EMT) has an important role in the development of embryo, as well as that in the metastasis of non-small cell lung cancer (NSCLC). Recent researches have demonstrated that both morphological and phenotypic conversions emerge in cells undergoing EMT. As most of relevant studies were on other cancers, it is essential to uncover whether it is the similar mechanisms accounting for EMT in NSCLC. With the progress of the studies, EMT-related basic researches are gradually applied to predicting the prognosis of NSCLC. The aim of this article was to discuss the mechanisms related to EMT emerging in NSCLC. 中国肺癌杂志编辑部 2014-07-20 /pmc/articles/PMC6000464/ /pubmed/25034589 http://dx.doi.org/10.3779/j.issn.1009-3419.2014.07.13 Text en 版权所有©《中国肺癌杂志》编辑部2014 https://creativecommons.org/licenses/by/3.0/ This is an open access article distributed in accordance with the terms of the Creative Commons Attribution (CC BY 3.0) License. See: https://creativecommons.org/licenses/by/3.0/ |
spellingShingle | 综述 非小细胞肺癌中EMT的发生机制及预后价值的研究进展 |
title | 非小细胞肺癌中EMT的发生机制及预后价值的研究进展 |
title_full | 非小细胞肺癌中EMT的发生机制及预后价值的研究进展 |
title_fullStr | 非小细胞肺癌中EMT的发生机制及预后价值的研究进展 |
title_full_unstemmed | 非小细胞肺癌中EMT的发生机制及预后价值的研究进展 |
title_short | 非小细胞肺癌中EMT的发生机制及预后价值的研究进展 |
title_sort | 非小细胞肺癌中emt的发生机制及预后价值的研究进展 |
topic | 综述 |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6000464/ https://www.ncbi.nlm.nih.gov/pubmed/25034589 http://dx.doi.org/10.3779/j.issn.1009-3419.2014.07.13 |
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