Akt在非小细胞肺癌中作用的研究现状

Lung cancer is one of the most common malignant tumors in the world, but its pathogenesis has still been remaining confusing. As an important protein in several signaling pathways, Akt has been identified to play a major role in the growth, proliferation, apoptosis and invasion of tumor cells. This...

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Detalles Bibliográficos
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 中国肺癌杂志编辑部 2010
Materias:
综述
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6000488/
https://www.ncbi.nlm.nih.gov/pubmed/21081049
http://dx.doi.org/10.3779/j.issn.1009-3419.2010.11.12
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description Lung cancer is one of the most common malignant tumors in the world, but its pathogenesis has still been remaining confusing. As an important protein in several signaling pathways, Akt has been identified to play a major role in the growth, proliferation, apoptosis and invasion of tumor cells. This paper is to review the effects of Akt, together with PDK1, Raf-1 and p70S6K, which are upstream and downstream regulatory molecules of Akt, and provide a new basis for the pathogenesis of non-small cell lung cancer.
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spelling pubmed-60004882018-07-06 Akt在非小细胞肺癌中作用的研究现状 Zhongguo Fei Ai Za Zhi 综述 Lung cancer is one of the most common malignant tumors in the world, but its pathogenesis has still been remaining confusing. As an important protein in several signaling pathways, Akt has been identified to play a major role in the growth, proliferation, apoptosis and invasion of tumor cells. This paper is to review the effects of Akt, together with PDK1, Raf-1 and p70S6K, which are upstream and downstream regulatory molecules of Akt, and provide a new basis for the pathogenesis of non-small cell lung cancer. 中国肺癌杂志编辑部 2010-11-20 /pmc/articles/PMC6000488/ /pubmed/21081049 http://dx.doi.org/10.3779/j.issn.1009-3419.2010.11.12 Text en 版权所有©《中国肺癌杂志》编辑部2010 https://creativecommons.org/licenses/by/3.0/ This is an open access article distributed in accordance with the terms of the Creative Commons Attribution (CC BY 3.0) License. See: https://creativecommons.org/licenses/by/3.0/
spellingShingle 综述
Akt在非小细胞肺癌中作用的研究现状
title Akt在非小细胞肺癌中作用的研究现状
title_full Akt在非小细胞肺癌中作用的研究现状
title_fullStr Akt在非小细胞肺癌中作用的研究现状
title_full_unstemmed Akt在非小细胞肺癌中作用的研究现状
title_short Akt在非小细胞肺癌中作用的研究现状
title_sort akt在非小细胞肺癌中作用的研究现状
topic 综述
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6000488/
https://www.ncbi.nlm.nih.gov/pubmed/21081049
http://dx.doi.org/10.3779/j.issn.1009-3419.2010.11.12

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