肺癌靶向药物肝脏毒性作用研究进展

Targeted drugs aimed at driver gene, such as Geftinib, Erlotinib and Crizotinib, have an irreplaceable position in the therapy of advanced non-small cell lung cancer. Tese drugs bring beneft to patients, however, higher hepatotoxicity is also presented. Now, drug induced hepatotoxicity and its mecha...

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Detalles Bibliográficos
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 中国肺癌杂志编辑部 2014
Materias:
综述
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6000506/
https://www.ncbi.nlm.nih.gov/pubmed/25248711
http://dx.doi.org/10.3779/j.issn.1009-3419.2014.09.08
Descripción
Sumario:Targeted drugs aimed at driver gene, such as Geftinib, Erlotinib and Crizotinib, have an irreplaceable position in the therapy of advanced non-small cell lung cancer. Tese drugs bring beneft to patients, however, higher hepatotoxicity is also presented. Now, drug induced hepatotoxicity and its mechanism are reviewed.

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