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Goblet cell carcinoid of the appendix: Case report of a high grade tumor in a 20-year-old
INTRODUCTION: Goblet cell carcinoid (GCC) is an extraordinarily rare appendiceal tumor that is usually an incidental diagnosis on post-operative histology. It typically presents in the fifth or sixth decade of life. Our patient is the only reported case study of GCC in a pediatric-young adult. Due t...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6000770/ https://www.ncbi.nlm.nih.gov/pubmed/29698881 http://dx.doi.org/10.1016/j.ijscr.2018.04.011 |
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author | Barghi, Ameen Grabbe, John Ghosh, Arundhati |
author_facet | Barghi, Ameen Grabbe, John Ghosh, Arundhati |
author_sort | Barghi, Ameen |
collection | PubMed |
description | INTRODUCTION: Goblet cell carcinoid (GCC) is an extraordinarily rare appendiceal tumor that is usually an incidental diagnosis on post-operative histology. It typically presents in the fifth or sixth decade of life. Our patient is the only reported case study of GCC in a pediatric-young adult. Due to its potentially poor prognosis, GCC is surgically treated as an adenocarcinoma, with right hemicolectomy as the mainstay of treatment. PRESENTATION OF CASE: The patient was a 20-year-old male who presented with a history, physical exam, and work up consistent with acute appendicitis. He underwent an uneventful laparoscopic appendectomy and was diagnosed with a high grade GCC post-operatively. DISCUSSION: GCC is a rare tumor of the appendix with unique histological features including small rosettes with crescentic nuclei distended with mucin. It is often retroactively diagnosed with histology after a majority of patients present with acute appendicitis symptoms. The behavior of this tumor in pediatric-young adults is very poorly understood. CONCLUSION: We review the literature for GCC of the appendix and illustrate a case report of a young, otherwise healthy 20-year-old who presented as appendicitis. Although rare, neoplasm must be kept in mind while offering non-operative management for acute appendicitis. |
format | Online Article Text |
id | pubmed-6000770 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2018 |
publisher | Elsevier |
record_format | MEDLINE/PubMed |
spelling | pubmed-60007702018-06-15 Goblet cell carcinoid of the appendix: Case report of a high grade tumor in a 20-year-old Barghi, Ameen Grabbe, John Ghosh, Arundhati Int J Surg Case Rep Article INTRODUCTION: Goblet cell carcinoid (GCC) is an extraordinarily rare appendiceal tumor that is usually an incidental diagnosis on post-operative histology. It typically presents in the fifth or sixth decade of life. Our patient is the only reported case study of GCC in a pediatric-young adult. Due to its potentially poor prognosis, GCC is surgically treated as an adenocarcinoma, with right hemicolectomy as the mainstay of treatment. PRESENTATION OF CASE: The patient was a 20-year-old male who presented with a history, physical exam, and work up consistent with acute appendicitis. He underwent an uneventful laparoscopic appendectomy and was diagnosed with a high grade GCC post-operatively. DISCUSSION: GCC is a rare tumor of the appendix with unique histological features including small rosettes with crescentic nuclei distended with mucin. It is often retroactively diagnosed with histology after a majority of patients present with acute appendicitis symptoms. The behavior of this tumor in pediatric-young adults is very poorly understood. CONCLUSION: We review the literature for GCC of the appendix and illustrate a case report of a young, otherwise healthy 20-year-old who presented as appendicitis. Although rare, neoplasm must be kept in mind while offering non-operative management for acute appendicitis. Elsevier 2018-04-16 /pmc/articles/PMC6000770/ /pubmed/29698881 http://dx.doi.org/10.1016/j.ijscr.2018.04.011 Text en © 2018 The Authors http://creativecommons.org/licenses/by-nc-nd/4.0/ This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/). |
spellingShingle | Article Barghi, Ameen Grabbe, John Ghosh, Arundhati Goblet cell carcinoid of the appendix: Case report of a high grade tumor in a 20-year-old |
title | Goblet cell carcinoid of the appendix: Case report of a high grade tumor in a 20-year-old |
title_full | Goblet cell carcinoid of the appendix: Case report of a high grade tumor in a 20-year-old |
title_fullStr | Goblet cell carcinoid of the appendix: Case report of a high grade tumor in a 20-year-old |
title_full_unstemmed | Goblet cell carcinoid of the appendix: Case report of a high grade tumor in a 20-year-old |
title_short | Goblet cell carcinoid of the appendix: Case report of a high grade tumor in a 20-year-old |
title_sort | goblet cell carcinoid of the appendix: case report of a high grade tumor in a 20-year-old |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6000770/ https://www.ncbi.nlm.nih.gov/pubmed/29698881 http://dx.doi.org/10.1016/j.ijscr.2018.04.011 |
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