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The Detection and Phylogenetic Analysis of Bovine Hepacivirus in China
Hepacivirus has been identified in cattle in Africa, Europe, and South America. In this survey of bovine hepacivirus (BovHepV) in 131 serum samples from Chinese cattle herds using RT-PCR, five of 131 sera were BovHepV positive, with the infection rate of 3.82%. Phylogenetic analysis based on the par...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6000834/ https://www.ncbi.nlm.nih.gov/pubmed/29955606 http://dx.doi.org/10.1155/2018/6216853 |
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author | Deng, Yu Guan, Su Hua Wang, Silu Hao, Guiying Rasmussen, Thomas Bruun |
author_facet | Deng, Yu Guan, Su Hua Wang, Silu Hao, Guiying Rasmussen, Thomas Bruun |
author_sort | Deng, Yu |
collection | PubMed |
description | Hepacivirus has been identified in cattle in Africa, Europe, and South America. In this survey of bovine hepacivirus (BovHepV) in 131 serum samples from Chinese cattle herds using RT-PCR, five of 131 sera were BovHepV positive, with the infection rate of 3.82%. Phylogenetic analysis based on the partial NS3 coding sequence showed that the BovHepV of the five positive samples clustered with other BovHepV but formed a separate branch. The results indicated that these new BovHepV represent emerging and novel strains. Further investigations are necessary to determine the epidemiology and viral pathogenesis of these BovHepV strains, as well as the potential threat to ruminant and livestock workers in China. |
format | Online Article Text |
id | pubmed-6000834 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2018 |
publisher | Hindawi |
record_format | MEDLINE/PubMed |
spelling | pubmed-60008342018-06-28 The Detection and Phylogenetic Analysis of Bovine Hepacivirus in China Deng, Yu Guan, Su Hua Wang, Silu Hao, Guiying Rasmussen, Thomas Bruun Biomed Res Int Research Article Hepacivirus has been identified in cattle in Africa, Europe, and South America. In this survey of bovine hepacivirus (BovHepV) in 131 serum samples from Chinese cattle herds using RT-PCR, five of 131 sera were BovHepV positive, with the infection rate of 3.82%. Phylogenetic analysis based on the partial NS3 coding sequence showed that the BovHepV of the five positive samples clustered with other BovHepV but formed a separate branch. The results indicated that these new BovHepV represent emerging and novel strains. Further investigations are necessary to determine the epidemiology and viral pathogenesis of these BovHepV strains, as well as the potential threat to ruminant and livestock workers in China. Hindawi 2018-05-31 /pmc/articles/PMC6000834/ /pubmed/29955606 http://dx.doi.org/10.1155/2018/6216853 Text en Copyright © 2018 Yu Deng et al. https://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Research Article Deng, Yu Guan, Su Hua Wang, Silu Hao, Guiying Rasmussen, Thomas Bruun The Detection and Phylogenetic Analysis of Bovine Hepacivirus in China |
title | The Detection and Phylogenetic Analysis of Bovine Hepacivirus in China |
title_full | The Detection and Phylogenetic Analysis of Bovine Hepacivirus in China |
title_fullStr | The Detection and Phylogenetic Analysis of Bovine Hepacivirus in China |
title_full_unstemmed | The Detection and Phylogenetic Analysis of Bovine Hepacivirus in China |
title_short | The Detection and Phylogenetic Analysis of Bovine Hepacivirus in China |
title_sort | detection and phylogenetic analysis of bovine hepacivirus in china |
topic | Research Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6000834/ https://www.ncbi.nlm.nih.gov/pubmed/29955606 http://dx.doi.org/10.1155/2018/6216853 |
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