Cargando…

Successful Treatment of Actinic Keratosis with Kanuka Honey

Actinic keratoses form as rough, scaly plaques on sun-exposed areas; they can be an important step in premalignant progression to squamous cell cancer of the skin. Currently, pharmacological treatments consist of topical immunomodulatory agents with poor side effect profiles. Use of honey has been c...

Descripción completa

Detalles Bibliográficos
Autores principales: Mane, Saras, Singer, Joseph, Corin, Andrew, Semprini, Alex
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6000848/
https://www.ncbi.nlm.nih.gov/pubmed/29955399
http://dx.doi.org/10.1155/2018/4628971
_version_ 1783331844369940480
author Mane, Saras
Singer, Joseph
Corin, Andrew
Semprini, Alex
author_facet Mane, Saras
Singer, Joseph
Corin, Andrew
Semprini, Alex
author_sort Mane, Saras
collection PubMed
description Actinic keratoses form as rough, scaly plaques on sun-exposed areas; they can be an important step in premalignant progression to squamous cell cancer of the skin. Currently, pharmacological treatments consist of topical immunomodulatory agents with poor side effect profiles. Use of honey has been common in both ancient and modern medicine, where it is now a key therapy in the management of wound healing. In vitro studies show the New Zealand native Kanuka honey to have immunomodulatory and antimitotic effects, with recent evidence suggesting efficacy of topical application in a variety of dermatological contexts, including rosacea and psoriasis. Here, we present a case report of a 66-year-old gentleman with an actinic keratosis on his hand, which had been present for years. Regular application of Kanuka honey over three months resulted in remission immediately following the treatment period with no signs of recurrence at nine months.
format Online
Article
Text
id pubmed-6000848
institution National Center for Biotechnology Information
language English
publishDate 2018
publisher Hindawi
record_format MEDLINE/PubMed
spelling pubmed-60008482018-06-28 Successful Treatment of Actinic Keratosis with Kanuka Honey Mane, Saras Singer, Joseph Corin, Andrew Semprini, Alex Case Rep Dermatol Med Case Report Actinic keratoses form as rough, scaly plaques on sun-exposed areas; they can be an important step in premalignant progression to squamous cell cancer of the skin. Currently, pharmacological treatments consist of topical immunomodulatory agents with poor side effect profiles. Use of honey has been common in both ancient and modern medicine, where it is now a key therapy in the management of wound healing. In vitro studies show the New Zealand native Kanuka honey to have immunomodulatory and antimitotic effects, with recent evidence suggesting efficacy of topical application in a variety of dermatological contexts, including rosacea and psoriasis. Here, we present a case report of a 66-year-old gentleman with an actinic keratosis on his hand, which had been present for years. Regular application of Kanuka honey over three months resulted in remission immediately following the treatment period with no signs of recurrence at nine months. Hindawi 2018-05-31 /pmc/articles/PMC6000848/ /pubmed/29955399 http://dx.doi.org/10.1155/2018/4628971 Text en Copyright © 2018 Saras Mane et al. https://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Mane, Saras
Singer, Joseph
Corin, Andrew
Semprini, Alex
Successful Treatment of Actinic Keratosis with Kanuka Honey
title Successful Treatment of Actinic Keratosis with Kanuka Honey
title_full Successful Treatment of Actinic Keratosis with Kanuka Honey
title_fullStr Successful Treatment of Actinic Keratosis with Kanuka Honey
title_full_unstemmed Successful Treatment of Actinic Keratosis with Kanuka Honey
title_short Successful Treatment of Actinic Keratosis with Kanuka Honey
title_sort successful treatment of actinic keratosis with kanuka honey
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6000848/
https://www.ncbi.nlm.nih.gov/pubmed/29955399
http://dx.doi.org/10.1155/2018/4628971
work_keys_str_mv AT manesaras successfultreatmentofactinickeratosiswithkanukahoney
AT singerjoseph successfultreatmentofactinickeratosiswithkanukahoney
AT corinandrew successfultreatmentofactinickeratosiswithkanukahoney
AT semprinialex successfultreatmentofactinickeratosiswithkanukahoney