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Current Challenges in Delivery and Cytosolic Translocation of Therapeutic RNAs
RNA interference (RNAi) is a fundamental cellular process for the posttranscriptional regulation of gene expression. RNAi can exogenously be modulated by small RNA oligonucleotides, such as microRNAs (miRNAs) and small interfering RNAs (siRNAs), or by antisense oligonucleotides. These small oligonuc...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Mary Ann Liebert, Inc.
2018
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6000866/ https://www.ncbi.nlm.nih.gov/pubmed/29883296 http://dx.doi.org/10.1089/nat.2017.0716 |