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Co-stimulation of LPAR(1) and S1PR(1/3) increases the transplantation efficacy of human mesenchymal stem cells in drug-induced and alcoholic liver diseases

BACKGROUND: One of the major obstacles facing stem cell therapy is the limited number of functional stem cells available after transplantation due to the harsh microenvironment surrounding the damaged tissue. The aim of this study was to delineate the mechanistic involvement of lysophosphatidic acid...

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Detalles Bibliográficos
Autores principales: Li, Mianhuan, Lv, Yi, Chen, Feng, Wang, Xiaoyan, Zhu, Jiang, Li, Hao, Xiao, Jia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6000942/
https://www.ncbi.nlm.nih.gov/pubmed/29898789
http://dx.doi.org/10.1186/s13287-018-0860-y