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The impact of bariatric surgery on the resolution of obstructive sleep apnoea

OBJECTIVE: Obesity is associated with a high incidence of obstructive sleep apnoea (OSA). Bariatric surgery is postulated to lead to OSA resolution, but there is inconclusive evidence on its efficacy. We used objective measurements to determine the rate of resolution or improvement of OSA in patient...

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Autores principales: Sillo, Toritseju Oluwafunmilayo, Lloyd-Owen, Simon, White, Emma, Abolghasemi-Malekabadi, Karen, Lock-Pullan, Penny, Ali, Muhammed, Perry, Anthony, Robinson, Steven John, Wadley, Martin Stuart
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6000945/
https://www.ncbi.nlm.nih.gov/pubmed/29898772
http://dx.doi.org/10.1186/s13104-018-3484-5
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author Sillo, Toritseju Oluwafunmilayo
Lloyd-Owen, Simon
White, Emma
Abolghasemi-Malekabadi, Karen
Lock-Pullan, Penny
Ali, Muhammed
Perry, Anthony
Robinson, Steven John
Wadley, Martin Stuart
author_facet Sillo, Toritseju Oluwafunmilayo
Lloyd-Owen, Simon
White, Emma
Abolghasemi-Malekabadi, Karen
Lock-Pullan, Penny
Ali, Muhammed
Perry, Anthony
Robinson, Steven John
Wadley, Martin Stuart
author_sort Sillo, Toritseju Oluwafunmilayo
collection PubMed
description OBJECTIVE: Obesity is associated with a high incidence of obstructive sleep apnoea (OSA). Bariatric surgery is postulated to lead to OSA resolution, but there is inconclusive evidence on its efficacy. We used objective measurements to determine the rate of resolution or improvement of OSA in patients who had bariatric procedures in our unit. RESULTS: Data was analysed on all patients with OSA who underwent bariatric procedures [laparoscopic Roux-en-Y gastric bypass (LRYGB) and sleeve gastrectomy (LSG)] between June 2012 and September 2016 in our unit. 47 patients (26.7%) were diagnosed with OSA. Mean age was 48.5 years. 63.8% were female. 43 required nocturnal continuous positive airway pressure (CPAP) support. Procedures were LRYGB (n = 26) and LSG (n = 21). Mean excess weight loss was 56.1%. Mean start apnoea-hypopnoea index (AHI) on CPAP was 6.4 events/hr and end AHI was 1.4 events/h. 14 patients (32.6%) had complete OSA resolution and 12 (27.9%) showed improvement in pressure support requirements. We demonstrated that 55.3% of patients had resolution or improvement in OSA following bariatric surgery. However, there was a high rate of non-attendance of follow-up appointments. Future efforts will involve analysis of the reasons for this to ensure more robust monitoring.
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spelling pubmed-60009452018-06-25 The impact of bariatric surgery on the resolution of obstructive sleep apnoea Sillo, Toritseju Oluwafunmilayo Lloyd-Owen, Simon White, Emma Abolghasemi-Malekabadi, Karen Lock-Pullan, Penny Ali, Muhammed Perry, Anthony Robinson, Steven John Wadley, Martin Stuart BMC Res Notes Research Note OBJECTIVE: Obesity is associated with a high incidence of obstructive sleep apnoea (OSA). Bariatric surgery is postulated to lead to OSA resolution, but there is inconclusive evidence on its efficacy. We used objective measurements to determine the rate of resolution or improvement of OSA in patients who had bariatric procedures in our unit. RESULTS: Data was analysed on all patients with OSA who underwent bariatric procedures [laparoscopic Roux-en-Y gastric bypass (LRYGB) and sleeve gastrectomy (LSG)] between June 2012 and September 2016 in our unit. 47 patients (26.7%) were diagnosed with OSA. Mean age was 48.5 years. 63.8% were female. 43 required nocturnal continuous positive airway pressure (CPAP) support. Procedures were LRYGB (n = 26) and LSG (n = 21). Mean excess weight loss was 56.1%. Mean start apnoea-hypopnoea index (AHI) on CPAP was 6.4 events/hr and end AHI was 1.4 events/h. 14 patients (32.6%) had complete OSA resolution and 12 (27.9%) showed improvement in pressure support requirements. We demonstrated that 55.3% of patients had resolution or improvement in OSA following bariatric surgery. However, there was a high rate of non-attendance of follow-up appointments. Future efforts will involve analysis of the reasons for this to ensure more robust monitoring. BioMed Central 2018-06-14 /pmc/articles/PMC6000945/ /pubmed/29898772 http://dx.doi.org/10.1186/s13104-018-3484-5 Text en © The Author(s) 2018 Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.
spellingShingle Research Note
Sillo, Toritseju Oluwafunmilayo
Lloyd-Owen, Simon
White, Emma
Abolghasemi-Malekabadi, Karen
Lock-Pullan, Penny
Ali, Muhammed
Perry, Anthony
Robinson, Steven John
Wadley, Martin Stuart
The impact of bariatric surgery on the resolution of obstructive sleep apnoea
title The impact of bariatric surgery on the resolution of obstructive sleep apnoea
title_full The impact of bariatric surgery on the resolution of obstructive sleep apnoea
title_fullStr The impact of bariatric surgery on the resolution of obstructive sleep apnoea
title_full_unstemmed The impact of bariatric surgery on the resolution of obstructive sleep apnoea
title_short The impact of bariatric surgery on the resolution of obstructive sleep apnoea
title_sort impact of bariatric surgery on the resolution of obstructive sleep apnoea
topic Research Note
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6000945/
https://www.ncbi.nlm.nih.gov/pubmed/29898772
http://dx.doi.org/10.1186/s13104-018-3484-5
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