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Generation of HER2-specific antibody immunity during trastuzumab adjuvant therapy associates with reduced relapse in resected HER2 breast cancer
BACKGROUND: Resected HER2 breast cancer patients treated with adjuvant trastuzumab and chemotherapy have superior survival compared to patients treated with chemotherapy alone. We previously showed that trastuzumab and chemotherapy induce HER2-specific antibodies which correlate with improved surviv...
Autores principales: | Norton, Nadine, Fox, Nicholas, McCarl, Christie-Ann, Tenner, Kathleen S., Ballman, Karla, Erskine, Courtney L., Necela, Brian M., Northfelt, Donald, Tan, Winston W., Calfa, Carmen, Pegram, Mark, Colon-Otero, Gerardo, Perez, Edith A., Clynes, Raphael, Knutson, Keith L. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6000975/ https://www.ncbi.nlm.nih.gov/pubmed/29898752 http://dx.doi.org/10.1186/s13058-018-0989-8 |
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