Expression of human CD46 and trans-complementation by murine adenovirus 1 fails to allow productive infection by a group B oncolytic adenovirus in murine cancer cells

BACKGROUND: Oncolytic viruses are currently experiencing accelerated development in several laboratories worldwide, with some forty-seven clinical trials currently recruiting. Many oncolytic viruses combine targeted cytotoxicity to cancer cells with a proinflammatory cell lysis. Due to their additio...

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Detalles Bibliográficos
Autores principales: Lei, Janet, Jacobus, Egon J., Taverner, William K., Fisher, Kerry D., Hemmi, Silvio, West, Katy, Slater, Lorna, Lilley, Fred, Brown, Alice, Champion, Brian, Duffy, Margaret R., Seymour, Len W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6000980/
https://www.ncbi.nlm.nih.gov/pubmed/29898782
http://dx.doi.org/10.1186/s40425-018-0350-x

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