Tropylium-promoted carbonyl–olefin metathesis reactions

The carbonyl–olefin metathesis (COM) reaction is a highly valuable chemical transformation in a broad range of applications. However, its scope is much less explored compared to analogous olefin–olefin metathesis reactions. Herein we demonstrate the use of tropylium ion as a new effective organic Le...

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Autores principales: Tran, Uyen P. N., Oss, Giulia, Pace, Domenic P., Ho, Junming, Nguyen, Thanh V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Royal Society of Chemistry 2018
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6000984/
https://www.ncbi.nlm.nih.gov/pubmed/29997866
http://dx.doi.org/10.1039/c8sc00907d
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author Tran, Uyen P. N.
Oss, Giulia
Pace, Domenic P.
Ho, Junming
Nguyen, Thanh V.
author_facet Tran, Uyen P. N.
Oss, Giulia
Pace, Domenic P.
Ho, Junming
Nguyen, Thanh V.
author_sort Tran, Uyen P. N.
collection PubMed
description The carbonyl–olefin metathesis (COM) reaction is a highly valuable chemical transformation in a broad range of applications. However, its scope is much less explored compared to analogous olefin–olefin metathesis reactions. Herein we demonstrate the use of tropylium ion as a new effective organic Lewis acid catalyst for both intramolecular and intermolecular COM and new ring-opening metathesis reactions. This represents a significant improvement in substrate scope from recently reported developments in this field.
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spelling pubmed-60009842018-07-11 Tropylium-promoted carbonyl–olefin metathesis reactions Tran, Uyen P. N. Oss, Giulia Pace, Domenic P. Ho, Junming Nguyen, Thanh V. Chem Sci Chemistry The carbonyl–olefin metathesis (COM) reaction is a highly valuable chemical transformation in a broad range of applications. However, its scope is much less explored compared to analogous olefin–olefin metathesis reactions. Herein we demonstrate the use of tropylium ion as a new effective organic Lewis acid catalyst for both intramolecular and intermolecular COM and new ring-opening metathesis reactions. This represents a significant improvement in substrate scope from recently reported developments in this field. Royal Society of Chemistry 2018-05-04 /pmc/articles/PMC6000984/ /pubmed/29997866 http://dx.doi.org/10.1039/c8sc00907d Text en This journal is © The Royal Society of Chemistry 2018 https://creativecommons.org/licenses/by-nc/3.0/This article is freely available. This article is licensed under a Creative Commons Attribution Non Commercial 3.0 Unported Licence (CC BY-NC 3.0)
spellingShingle Chemistry
Tran, Uyen P. N.
Oss, Giulia
Pace, Domenic P.
Ho, Junming
Nguyen, Thanh V.
Tropylium-promoted carbonyl–olefin metathesis reactions
title Tropylium-promoted carbonyl–olefin metathesis reactions
title_full Tropylium-promoted carbonyl–olefin metathesis reactions
title_fullStr Tropylium-promoted carbonyl–olefin metathesis reactions
title_full_unstemmed Tropylium-promoted carbonyl–olefin metathesis reactions
title_short Tropylium-promoted carbonyl–olefin metathesis reactions
title_sort tropylium-promoted carbonyl–olefin metathesis reactions
topic Chemistry
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6000984/
https://www.ncbi.nlm.nih.gov/pubmed/29997866
http://dx.doi.org/10.1039/c8sc00907d
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