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Sleeping Beauty and the Microenvironment Enchantment: Microenvironmental Regulation of the Proliferation-Quiescence Decision in Normal Tissues and in Cancer Development
Cells from prokaryota to the more complex metazoans cease proliferating at some point in their lives and enter a reversible, proliferative-dormant state termed quiescence. The appearance of quiescence in the course of evolution was essential to the acquisition of multicellular specialization and com...
Autores principales: | Fiore, Ana Paula Zen Petisco, Ribeiro, Pedro de Freitas, Bruni-Cardoso, Alexandre |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6001001/ https://www.ncbi.nlm.nih.gov/pubmed/29930939 http://dx.doi.org/10.3389/fcell.2018.00059 |
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