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Prevalence of dermatological complaints in patients undergoing treatment for breast cancer

BACKGROUND: Internal malignancies such as breast cancer, as well as their treatment can often result in skin changes. OBJECTIVE: To assess the prevalence of dermatological complaints in patients who are undergoing oncological treatment for breast cancer in a hospital in Tubarão, Santa Catarina, Braz...

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Autores principales: Hoffmann, Tamara, Corrêa-Fissmer, Mariane, Duarte, Camila Soares, Nazário, Rayane Felippe, Barranco, Ana Beatriz Sanches, de Oliveira, Karen Waleska Knipoff
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Sociedade Brasileira de Dermatologia 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6001084/
https://www.ncbi.nlm.nih.gov/pubmed/29924229
http://dx.doi.org/10.1590/abd1806-4841.20186541
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author Hoffmann, Tamara
Corrêa-Fissmer, Mariane
Duarte, Camila Soares
Nazário, Rayane Felippe
Barranco, Ana Beatriz Sanches
de Oliveira, Karen Waleska Knipoff
author_facet Hoffmann, Tamara
Corrêa-Fissmer, Mariane
Duarte, Camila Soares
Nazário, Rayane Felippe
Barranco, Ana Beatriz Sanches
de Oliveira, Karen Waleska Knipoff
author_sort Hoffmann, Tamara
collection PubMed
description BACKGROUND: Internal malignancies such as breast cancer, as well as their treatment can often result in skin changes. OBJECTIVE: To assess the prevalence of dermatological complaints in patients who are undergoing oncological treatment for breast cancer in a hospital in Tubarão, Santa Catarina, Brazil. METHODS: Observational, cross-sectional study, from October 2015 to February 2016 in which 152 patients with the diagnosis of breast cancer, undergoing treatment with chemotherapy, radiotherapy, hormone therapy and/or surgery, were interviewed and completed a research protocol developed by the author. RESULTS: The treatment of breast cancer was associated with dermatological complaints in 94.1% of the interviewed, being with hair loss the most frequent, present in 79.6% of the sample, followed by nail changes (56%). Patients with lighter skin phototypes (I, II and III) had a lower risk (p=0.045) of developing skin changes when compared to darker phototypes. Radiation therapy (p=0.011) and oncological surgery (pFisher=0.004) were statistically significant when related to skin changes. STUDY LIMITATIONS: Inherent to the design of the study, as well as recall bias. CONCLUSIONS: It was found that most patients diagnosed with breast cancer showed dermatologic manifestations during the proposed cancer treatment. Patients undergoing radiotherapy and surgery showed skin changes with greater statistical significance.
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spelling pubmed-60010842018-06-19 Prevalence of dermatological complaints in patients undergoing treatment for breast cancer Hoffmann, Tamara Corrêa-Fissmer, Mariane Duarte, Camila Soares Nazário, Rayane Felippe Barranco, Ana Beatriz Sanches de Oliveira, Karen Waleska Knipoff An Bras Dermatol Investigation BACKGROUND: Internal malignancies such as breast cancer, as well as their treatment can often result in skin changes. OBJECTIVE: To assess the prevalence of dermatological complaints in patients who are undergoing oncological treatment for breast cancer in a hospital in Tubarão, Santa Catarina, Brazil. METHODS: Observational, cross-sectional study, from October 2015 to February 2016 in which 152 patients with the diagnosis of breast cancer, undergoing treatment with chemotherapy, radiotherapy, hormone therapy and/or surgery, were interviewed and completed a research protocol developed by the author. RESULTS: The treatment of breast cancer was associated with dermatological complaints in 94.1% of the interviewed, being with hair loss the most frequent, present in 79.6% of the sample, followed by nail changes (56%). Patients with lighter skin phototypes (I, II and III) had a lower risk (p=0.045) of developing skin changes when compared to darker phototypes. Radiation therapy (p=0.011) and oncological surgery (pFisher=0.004) were statistically significant when related to skin changes. STUDY LIMITATIONS: Inherent to the design of the study, as well as recall bias. CONCLUSIONS: It was found that most patients diagnosed with breast cancer showed dermatologic manifestations during the proposed cancer treatment. Patients undergoing radiotherapy and surgery showed skin changes with greater statistical significance. Sociedade Brasileira de Dermatologia 2018 /pmc/articles/PMC6001084/ /pubmed/29924229 http://dx.doi.org/10.1590/abd1806-4841.20186541 Text en http://creativecommons.org/licenses/by-nc-nd/4.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial No Derivative License, which permits unrestricted non-commercial use, distribution, and reproduction in any medium provided the original work is properly cited and the work is not changed in any way.
spellingShingle Investigation
Hoffmann, Tamara
Corrêa-Fissmer, Mariane
Duarte, Camila Soares
Nazário, Rayane Felippe
Barranco, Ana Beatriz Sanches
de Oliveira, Karen Waleska Knipoff
Prevalence of dermatological complaints in patients undergoing treatment for breast cancer
title Prevalence of dermatological complaints in patients undergoing treatment for breast cancer
title_full Prevalence of dermatological complaints in patients undergoing treatment for breast cancer
title_fullStr Prevalence of dermatological complaints in patients undergoing treatment for breast cancer
title_full_unstemmed Prevalence of dermatological complaints in patients undergoing treatment for breast cancer
title_short Prevalence of dermatological complaints in patients undergoing treatment for breast cancer
title_sort prevalence of dermatological complaints in patients undergoing treatment for breast cancer
topic Investigation
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6001084/
https://www.ncbi.nlm.nih.gov/pubmed/29924229
http://dx.doi.org/10.1590/abd1806-4841.20186541
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