Cargando…

Generalized erythematous and scaly plaques and papules: a rare case of Rosai-Dorfman disease accompanied by multiple myeloma

A 75-year-old male presented with generalized erythematous, scaly plaques and painless lymphadenopathy. Rosai-Dorfman disease was suspected based on clinical manifestations and confirmed by histopathologic and immune reactivity studies performed on the biopsy obtained from the left supraclavicular l...

Descripción completa

Detalles Bibliográficos
Autores principales: Shafiee, Anoosh, Nasiri, Soheila
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Sociedade Brasileira de Dermatologia 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6001111/
https://www.ncbi.nlm.nih.gov/pubmed/29924217
http://dx.doi.org/10.1590/abd1806-4841.20187269
_version_ 1783331918363754496
author Shafiee, Anoosh
Nasiri, Soheila
author_facet Shafiee, Anoosh
Nasiri, Soheila
author_sort Shafiee, Anoosh
collection PubMed
description A 75-year-old male presented with generalized erythematous, scaly plaques and painless lymphadenopathy. Rosai-Dorfman disease was suspected based on clinical manifestations and confirmed by histopathologic and immune reactivity studies performed on the biopsy obtained from the left supraclavicular lymph node. The patient was also diagnosed with multiple myeloma according to urine electrophoresis, serum light chain assay, and bone marrow biopsy, which were initially performed for evaluation of anemia. This report highlights the dermatological manifestations of Rosai-Dorfman disease with generalized painless lymphadenopathy.
format Online
Article
Text
id pubmed-6001111
institution National Center for Biotechnology Information
language English
publishDate 2018
publisher Sociedade Brasileira de Dermatologia
record_format MEDLINE/PubMed
spelling pubmed-60011112018-06-19 Generalized erythematous and scaly plaques and papules: a rare case of Rosai-Dorfman disease accompanied by multiple myeloma Shafiee, Anoosh Nasiri, Soheila An Bras Dermatol Case Report A 75-year-old male presented with generalized erythematous, scaly plaques and painless lymphadenopathy. Rosai-Dorfman disease was suspected based on clinical manifestations and confirmed by histopathologic and immune reactivity studies performed on the biopsy obtained from the left supraclavicular lymph node. The patient was also diagnosed with multiple myeloma according to urine electrophoresis, serum light chain assay, and bone marrow biopsy, which were initially performed for evaluation of anemia. This report highlights the dermatological manifestations of Rosai-Dorfman disease with generalized painless lymphadenopathy. Sociedade Brasileira de Dermatologia 2018 /pmc/articles/PMC6001111/ /pubmed/29924217 http://dx.doi.org/10.1590/abd1806-4841.20187269 Text en http://creativecommons.org/licenses/by-nc-nd/4.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial No Derivative License, which permits unrestricted non-commercial use, distribution, and reproduction in any medium provided the original work is properly cited and the work is not changed in any way.
spellingShingle Case Report
Shafiee, Anoosh
Nasiri, Soheila
Generalized erythematous and scaly plaques and papules: a rare case of Rosai-Dorfman disease accompanied by multiple myeloma
title Generalized erythematous and scaly plaques and papules: a rare case of Rosai-Dorfman disease accompanied by multiple myeloma
title_full Generalized erythematous and scaly plaques and papules: a rare case of Rosai-Dorfman disease accompanied by multiple myeloma
title_fullStr Generalized erythematous and scaly plaques and papules: a rare case of Rosai-Dorfman disease accompanied by multiple myeloma
title_full_unstemmed Generalized erythematous and scaly plaques and papules: a rare case of Rosai-Dorfman disease accompanied by multiple myeloma
title_short Generalized erythematous and scaly plaques and papules: a rare case of Rosai-Dorfman disease accompanied by multiple myeloma
title_sort generalized erythematous and scaly plaques and papules: a rare case of rosai-dorfman disease accompanied by multiple myeloma
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6001111/
https://www.ncbi.nlm.nih.gov/pubmed/29924217
http://dx.doi.org/10.1590/abd1806-4841.20187269
work_keys_str_mv AT shafieeanoosh generalizederythematousandscalyplaquesandpapulesararecaseofrosaidorfmandiseaseaccompaniedbymultiplemyeloma
AT nasirisoheila generalizederythematousandscalyplaquesandpapulesararecaseofrosaidorfmandiseaseaccompaniedbymultiplemyeloma