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Down-regulation of microsomal prostaglandin E2 synthase-1 in the infrapatellar fat pad of osteoarthritis patients with hypercholesterolemia
BACKGROUND: While epidemiological studies have reported a potential role for hypercholesterolemia (HCE) in osteoarthritis (OA), the association between HCE and OA has yet to be clarified. Adipose tissue is a primary locus for cholesterol metabolism and the presence of HCE reportedly causes adipose d...
Autores principales: | Mukai, Manabu, Uchida, Kentaro, Takano, Shotaro, Iwase, Dai, Aikawa, Jun, Inoue, Gen, Miyagi, Masayuki, Takaso, Masashi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6001124/ https://www.ncbi.nlm.nih.gov/pubmed/29898737 http://dx.doi.org/10.1186/s12944-018-0792-7 |
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