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Transducin β-Subunit Can Interact with Multiple G-Protein γ-Subunits to Enable Light Detection by Rod Photoreceptors

The heterotrimeric G-protein transducin mediates visual signaling in vertebrate photoreceptor cells. Many aspects of the function of transducin were learned from knock-out mice lacking its individual subunits. Of particular interest is the knockout of its rod-specific γ-subunit (Gγ(1)). Two studies...

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Detalles Bibliográficos
Autores principales: Dexter, Paige M., Lobanova, Ekaterina S., Finkelstein, Stella, Spencer, William J., Skiba, Nikolai P., Arshavsky, Vadim Y.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Society for Neuroscience 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6001135/
https://www.ncbi.nlm.nih.gov/pubmed/29911170
http://dx.doi.org/10.1523/ENEURO.0144-18.2018