Cargando…

PD-L1 assessment in pediatric rhabdomyosarcoma: a pilot study

BACKGROUND: Rhabdomyosarcomas (RMSs) are the most frequent soft tissue sarcoma in children and adolescents, defined by skeletal muscle differentiation and the status of FOXO1 fusions. In pediatric malignancies, in particular RMS, scant and controversial observations are reported about PD-L1 expressi...

Descripción completa

Detalles Bibliográficos
Autores principales:	Bertolini, Giulia, Bergamaschi, Luca, Ferrari, Andrea, Renne, Salvatore L., Collini, Paola, Gardelli, Cecilia, Barisella, Marta, Centonze, Giovanni, Chiaravalli, Stefano, Paolino, Cinzia, Milione, Massimo, Massimino, Maura, Casanova, Michela, Gasparini, Patrizia
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2018
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6001160/ https://www.ncbi.nlm.nih.gov/pubmed/29898687 http://dx.doi.org/10.1186/s12885-018-4554-8

Ejemplares similares

Establishment of 6 pediatric rhabdomyosarcoma patient’s derived xenograft models closely recapitulating patients’ tumor characteristics
por: Gasparini, Patrizia, et al.
Publicado: (2022)

Age-Related Alterations in Immune Contexture Are Associated with Aggressiveness in Rhabdomyosarcoma
por: Gasparini, Patrizia, et al.
Publicado: (2019)

Anaplastic lymphoma kinase aberrations correlate with metastatic features in pediatric rhabdomyosarcoma
por: Gasparini, Patrizia, et al.
Publicado: (2016)

MiRNAs as Players in Rhabdomyosarcoma Development
por: Gasparini, Patrizia, et al.
Publicado: (2019)

Clinical Insight on Proton Therapy for Paediatric Rhabdomyosarcoma
por: Vennarini, Sabina, et al.
Publicado: (2023)

MiR-223 Exclusively Impairs In Vitro Tumor Growth through IGF1R Modulation in Rhabdomyosarcoma of Adolescents and Young Adults
por: Casanova, Michela, et al.
Publicado: (2022)

Model of Care for Adolescents and Young Adults with Cancer: The Youth Project in Milan
por: Magni, Chiara, et al.
Publicado: (2016)

Ultra Short Course Chemotherapy for Early-Stage Non-Hodgkin’s Lymphoma in Children
por: Schiavello, Elisabetta, et al.
Publicado: (2022)

Effectiveness of irinotecan plus trabectedin on a desmoplastic small round cell tumor patient-derived xenograft
por: Zuco, Valentina, et al.
Publicado: (2023)

Maintenance Chemotherapy for Patients with Rhabdomyosarcoma
por: Bisogno, Gianni, et al.
Publicado: (2023)

Pediatric Rhabdomyosarcomas: Three-Dimensional Radiological Assessments after Induction Chemotherapy Predict Survival Better than One-Dimensional and Two-Dimensional Measurements
por: Orsatti, Giovanna, et al.
Publicado: (2020)

Treating secondary malignant neoplasms: A burden of childhood cancer survivors
por: Podda, Marta G, et al.
Publicado: (2023)

Shedding a Light on the Challenges of Adolescents and Young Adults with Rhabdomyosarcoma
por: Ferrari, Andrea, et al.
Publicado: (2022)

Molecular Determinants of Soft Tissue Sarcoma Immunity: Targets for Immune Intervention
por: Tazzari, Marcella, et al.
Publicado: (2021)

Treatment at Relapse for Synovial Sarcoma of Children, Adolescents and Young Adults: From the State of Art to Future Clinical Perspectives
por: Ferrari, Andrea, et al.
Publicado: (2023)

Iron, Oxidative Damage and Ferroptosis in Rhabdomyosarcoma
por: Fanzani, Alessandro, et al.
Publicado: (2017)

Differential glycosylation of collagen modulates lung cancer stem cell subsets through β1 integrin‐mediated interactions
por: Gardelli, Cecilia, et al.
Publicado: (2020)

Secreting Germ Cell Tumors of the Central Nervous System: A Long-Term Follow-up Experience
por: Biassoni, Veronica, et al.
Publicado: (2020)

Managing Care during the COVID-19 Pandemic: The Point of View and Fears of Pediatric Cancer Patients’ Families
por: Nigro, Olga, et al.
Publicado: (2022)

Our young cancer patients talk—we learn
por: Ferrari, Andrea, et al.
Publicado: (2017)

Gastroblastoma in Adulthood—A Rarity among Rare Cancers—A Case Report and Review of the Literature
por: Centonze, Giovanni, et al.
Publicado: (2019)

The modulation of iron metabolism affects the Rhabdomyosarcoma tumor growth in vitro and in vivo
por: Asperti, Michela, et al.
Publicado: (2023)

A Perspective on Polo-Like Kinase-1 Inhibition for the Treatment of Rhabdomyosarcomas
por: Gatz, Susanne A., et al.
Publicado: (2019)

Cooperation of Oncolytic Herpes Virotherapy and PD-1 Blockade in Murine Rhabdomyosarcoma Models
por: Chen, Chun-Yu, et al.
Publicado: (2017)

Hyper-Activation of Notch3 Amplifies the Proliferative Potential of Rhabdomyosarcoma Cells
por: De Salvo, Maria, et al.
Publicado: (2014)

AKT1 and BRAF mutations in pediatric aggressive fibromatosis
por: Meazza, Cristina, et al.
Publicado: (2016)

Translational Implications for Radiosensitizing Strategies in Rhabdomyosarcoma
por: Pomella, Silvia, et al.
Publicado: (2022)

Cotargeting of miR‐126‐3p and miR‐221‐3p inhibits PIK3R2 and PTEN, reducing lung cancer growth and metastasis by blocking AKT and CXCR4 signalling
por: Di Paolo, Daniela, et al.
Publicado: (2021)

DAX-1 Expression in Pediatric Rhabdomyosarcomas: Another Immunohistochemical Marker Useful in the Diagnosis of Translocation Positive Alveolar Rhabdomyosarcoma
por: Virgone, Calogero, et al.
Publicado: (2015)

High Frequency of Tumor Propagating Cells in Fusion-Positive Rhabdomyosarcoma
por: Generali, Melanie, et al.
Publicado: (2021)

Long‐term survivors with desmoplastic small round cell tumor (DSRCT): Results from a retrospective single‐institution case series analysis
por: Giani, Claudia, et al.
Publicado: (2023)

Pediatric Non-Rhabdomyosarcoma Soft Tissue Sarcomas: Standard of Care and Treatment Recommendations from the European Paediatric Soft Tissue Sarcoma Study Group (EpSSG)
por: Ferrari, Andrea, et al.
Publicado: (2022)

Caveolins in rhabdomyosarcoma
por: Rossi, Stefania, et al.
Publicado: (2011)

Relapsed Rhabdomyosarcoma
por: Heske, Christine M., et al.
Publicado: (2021)

A large de novo 9p21.3 deletion in a girl affected by astrocytoma and multiple melanoma
por: Frigerio, Simona, et al.
Publicado: (2014)

Human Rhabdomyosarcoma Cell Lines for Rhabdomyosarcoma Research: Utility and Pitfalls
por: Hinson, Ashley R. P., et al.
Publicado: (2013)

YAP1 acts as oncogenic target of 11q22 amplification in multiple cancer subtypes
por: Lorenzetto, Erica, et al.
Publicado: (2014)

Vinorelbine and Intermittent Cyclophosphamide Sensitize an Aggressive Myc-Driven B-Cell Lymphoma to Anti-PD-1 by an Immunological Memory Effective against Tumor Re-Challenge
por: Orecchioni, Stefania, et al.
Publicado: (2023)

A homogeneous treatment for non-DIPG diffuse midline glioma
por: Schiavello, Elisabetta, et al.
Publicado: (2022)

Pediatric lung adenocarcinoma presenting with brain metastasis: a case report
por: De Martino, Lucia, et al.
Publicado: (2018)

Cannot write session to /tmp/vufind_sessions/sess_dqvr3441ddn8a3kdbfi1r345ho