Cargando…
Neural stem cell quiescence and stemness are molecularly distinct outputs of the Notch3 signalling cascade in the vertebrate adult brain
Neural stem cells (NSCs) in the adult vertebrate brain are found in a quiescent state and can preserve long-lasting progenitor potential (stemness). Whether and how these two properties are linked, and to what extent they can be independently controlled by NSC maintenance pathways, is unresolved. We...
Autores principales: | Than-Trong, Emmanuel, Ortica-Gatti, Sara, Mella, Sébastien, Nepal, Chirag, Alunni, Alessandro, Bally-Cuif, Laure |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Company of Biologists Ltd
2018
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6001379/ https://www.ncbi.nlm.nih.gov/pubmed/29695612 http://dx.doi.org/10.1242/dev.161034 |
Ejemplares similares
-
Lineage hierarchies and stochasticity ensure the long-term maintenance of adult neural stem cells
por: Than-Trong, Emmanuel, et al.
Publicado: (2020) -
DNA methylation safeguards the generation of hematopoietic stem and progenitor cells by repression of Notch signaling
por: Li, Yan, et al.
Publicado: (2022) -
Genes implicated in stem cell identity and temporal programme are directly targeted by Notch in neuroblast tumours
por: Zacharioudaki, Evanthia, et al.
Publicado: (2016) -
Stereotypical architecture of the stem cell niche is spatiotemporally established by miR-125-dependent coordination of Notch and steroid signaling
por: Yatsenko, Andriy S., et al.
Publicado: (2018) -
Notch-dependent DNA cis-regulatory elements and their dose-dependent control of C. elegans stem cell self-renewal
por: Lynch, Tina R., et al.
Publicado: (2022)