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Epoxygenase inactivation exacerbates diet and aging-associated metabolic dysfunction resulting from impaired adipogenesis

OBJECTIVE: When molecular drivers of healthy adipogenesis are perturbed, this can cause hepatic steatosis. The role of arachidonic acid (AA) and its downstream enzymatic cascades, such as cyclooxygenase, in adipogenesis is well established. The exact contribution of the P450 epoxygenase pathway, how...

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Detalles Bibliográficos
Autores principales:	Olona, Antoni, Terra, Ximena, Ko, Jeong-Hun, Grau-Bové, Carme, Pinent, Montserrat, Ardevol, Anna, Diaz, Ana Garcia, Moreno-Moral, Aida, Edin, Matthew, Bishop-Bailey, David, Zeldin, Darryl C., Aitman, Timothy J., Petretto, Enrico, Blay, Mayte, Behmoaras, Jacques
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2018
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6001407/ https://www.ncbi.nlm.nih.gov/pubmed/29656108 http://dx.doi.org/10.1016/j.molmet.2018.03.003

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