VEGF and GLUT1 are highly heritable, inversely correlated and affected by dietary fat intake: Consequences for cognitive function in humans

OBJECTIVE: Reduction of brain glucose transporter GLUT1 results in severe neurological dysfunction. VEGF is required to restore and maintain brain glucose uptake across the blood brain barrier via GLUT1, which was shown to be acutely diminished in response to a high fat diet (HFD) in mice. The genet...

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Detalles Bibliográficos
Autores principales: Schüler, Rita, Seebeck, Nicole, Osterhoff, Martin A., Witte, Veronica, Flöel, Agnes, Busjahn, Andreas, Jais, Alexander, Brüning, Jens C., Frahnow, Turid, Kabisch, Stefan, Pivovarova, Olga, Hornemann, Silke, Kruse, Michael, Pfeiffer, Andreas F.H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2018
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6001408/
https://www.ncbi.nlm.nih.gov/pubmed/29506909
http://dx.doi.org/10.1016/j.molmet.2018.02.004

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