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Inhibition of CRL-NEDD8 pathway as a new approach to enhance ATRA-induced differentiation of acute promyelocytic leukemia cells

The cullin-RING ligase (CRL)-NEDD8 pathway maintains essential cellular processes, including cell cycle progression, apoptosis, autophagy, DNA repair, antigen processing and signal transduction. Growing evidence demonstrates that the alteration of the CRL-NEDD8 pathway in some cancers constitutes an...

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Detalles Bibliográficos
Autores principales:	Liu, Shuyuan, Wan, Jinhua, Kong, Yunyuan, Zhang, Yonglu, Wan, Lagen, Zhang, Zhanglin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Ivyspring International Publisher 2018
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6001416/ https://www.ncbi.nlm.nih.gov/pubmed/29910671 http://dx.doi.org/10.7150/ijms.23782

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