Cargando…
Mir‐29b promotes human aortic valve interstitial cell calcification via inhibiting TGF‐β3 through activation of wnt3/β‐catenin/Smad3 signaling
Herein, we hypothesized that pro‐osteogenic MicroRNAs (miRs) could play functional roles in the calcification of the aortic valve and aimed to explore the functional role of miR‐29b in the osteoblastic differentiation of human aortic valve interstitial cells (hAVICs) and the underlying molecular mec...
Autores principales: | Fang, Ming, Wang, Cheng‐Guang, Zheng, Changzhu, Luo, Jun, Hou, Shiqiang, Liu, Kangyong, Li, Xinming |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2018
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6001435/ https://www.ncbi.nlm.nih.gov/pubmed/29227539 http://dx.doi.org/10.1002/jcb.26545 |
Ejemplares similares
-
Increased TGFβ1 and SMAD3 Contribute to Age-Related Aortic Valve Calcification
por: Chakrabarti, Mrinmay, et al.
Publicado: (2022) -
Niclosamide Inhibits Aortic Valve Interstitial Cell Calcification by Interfering with the GSK-3β/β-Catenin Signaling Pathway
por: Adhikari, Radhika, et al.
Publicado: (2023) -
Activation of Wnt/β‐catenin signalling is required for TGF‐β/Smad2/3 signalling during myofibroblast proliferation
por: Xu, Liang, et al.
Publicado: (2017) -
Lysyl hydroxylase 3 increases collagen deposition and promotes pulmonary fibrosis by activating TGFβ1/Smad3 and Wnt/β-catenin pathways
por: Shao, Songjun, et al.
Publicado: (2019) -
Catalpol Protects Against Pulmonary Fibrosis Through Inhibiting TGF-β1/Smad3 and Wnt/β-Catenin Signaling Pathways
por: Yang, Fan, et al.
Publicado: (2021)