Cargando…
Aneustat (OMN54) has aerobic glycolysis‐inhibitory activity and also immunomodulatory activity as indicated by a first‐generation PDX prostate cancer model
Aneustat (OMN54) is a multivalent, botanical anticancer candidate therapeutic. A recent Phase‐I clinical trial has indicated that it is well tolerated by patients and has immunomodulatory activity. In our study, using in vitro and in vivo prostate cancer models, we investigated Aneustat with regard...
Autores principales: | Qu, Sifeng, Xue, Hui, Dong, Xin, Lin, Dong, Wu, Rebecca, Nabavi, Noushin, Collins, Colin C., Gleave, Martin E., Gout, Peter W., Wang, Yuzhuo |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2018
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6001442/ https://www.ncbi.nlm.nih.gov/pubmed/29441566 http://dx.doi.org/10.1002/ijc.31310 |
Ejemplares similares
-
Enhanced anticancer activity of a combination of docetaxel and Aneustat (OMN54) in a patient‐derived, advanced prostate cancer tissue xenograft model
por: Qu, Sifeng, et al.
Publicado: (2013) -
Treatment with docetaxel in combination with Aneustat leads to potent inhibition of metastasis in a patient-derived xenograft model of advanced prostate cancer
por: Qu, Sifeng, et al.
Publicado: (2018) -
Targeting MCT4 to reduce lactic acid secretion and glycolysis for treatment of neuroendocrine prostate cancer
por: Choi, Stephen Yiu Chuen, et al.
Publicado: (2018) -
Heels: Et Id Omne Genus
por: Pratt, Ben. H.
Publicado: (1879) -
Activation of WNT/β‐catenin signaling results in resistance to a dual PI3K/mTOR inhibitor in colorectal cancer cells harboring PIK3CA mutations
por: Park, Ye‐Lim, et al.
Publicado: (2018)