Discontinuation and dose adjustment of metoprolol after metoprolol‐paroxetine/fluoxetine co‐prescription in Dutch elderly

PURPOSE: Co‐prescription of paroxetine/fluoxetine (a strong CYP2D6 inhibitor) in metoprolol (a CYP2D6 substrate) users is common, but data on the clinical consequences of this drug‐drug interaction are limited and inconclusive. Therefore, we assessed the effect of paroxetine/fluoxetine initiation on...

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Detalles Bibliográficos
Autores principales: Bahar, Muh. Akbar, Wang, Yuanyuan, Bos, Jens H.J., Wilffert, Bob, Hak, Eelko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Original Reports
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6001522/
https://www.ncbi.nlm.nih.gov/pubmed/29575226
http://dx.doi.org/10.1002/pds.4422

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6001522/
https://www.ncbi.nlm.nih.gov/pubmed/29575226
http://dx.doi.org/10.1002/pds.4422

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