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Discontinuation and dose adjustment of metoprolol after metoprolol‐paroxetine/fluoxetine co‐prescription in Dutch elderly
PURPOSE: Co‐prescription of paroxetine/fluoxetine (a strong CYP2D6 inhibitor) in metoprolol (a CYP2D6 substrate) users is common, but data on the clinical consequences of this drug‐drug interaction are limited and inconclusive. Therefore, we assessed the effect of paroxetine/fluoxetine initiation on...
Autores principales: | Bahar, Muh. Akbar, Wang, Yuanyuan, Bos, Jens H.J., Wilffert, Bob, Hak, Eelko |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6001522/ https://www.ncbi.nlm.nih.gov/pubmed/29575226 http://dx.doi.org/10.1002/pds.4422 |
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