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The neuroprotective role of melatonin in neurological disorders
Melatonin is a neurohormone secreted from the pineal gland and has a wide‐ranging regulatory and neuroprotective role. It has been reported that melatonin level is disturbed in some neurological conditions such as stroke, Alzheimer's disease, and Parkinson's disease, which indicates its in...
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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John Wiley and Sons Inc.
2018
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6001545/ https://www.ncbi.nlm.nih.gov/pubmed/29498103 http://dx.doi.org/10.1002/jnr.24220 |
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author | Alghamdi, B. S. |
author_facet | Alghamdi, B. S. |
author_sort | Alghamdi, B. S. |
collection | PubMed |
description | Melatonin is a neurohormone secreted from the pineal gland and has a wide‐ranging regulatory and neuroprotective role. It has been reported that melatonin level is disturbed in some neurological conditions such as stroke, Alzheimer's disease, and Parkinson's disease, which indicates its involvement in the pathophysiology of these diseases. Its properties qualify it to be a promising potential therapeutic neuroprotective agent, with no side effects, for some neurological disorders. This review discusses and localizes the effect of melatonin in the pathophysiology of some diseases. |
format | Online Article Text |
id | pubmed-6001545 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2018 |
publisher | John Wiley and Sons Inc. |
record_format | MEDLINE/PubMed |
spelling | pubmed-60015452018-06-21 The neuroprotective role of melatonin in neurological disorders Alghamdi, B. S. J Neurosci Res Reviews Melatonin is a neurohormone secreted from the pineal gland and has a wide‐ranging regulatory and neuroprotective role. It has been reported that melatonin level is disturbed in some neurological conditions such as stroke, Alzheimer's disease, and Parkinson's disease, which indicates its involvement in the pathophysiology of these diseases. Its properties qualify it to be a promising potential therapeutic neuroprotective agent, with no side effects, for some neurological disorders. This review discusses and localizes the effect of melatonin in the pathophysiology of some diseases. John Wiley and Sons Inc. 2018-03-01 2018-07 /pmc/articles/PMC6001545/ /pubmed/29498103 http://dx.doi.org/10.1002/jnr.24220 Text en © 2018 The Authors Journal of Neuroscience Research Published by Wiley Periodicals, Inc. This is an open access article under the terms of the http://creativecommons.org/licenses/by/4.0/ License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Reviews Alghamdi, B. S. The neuroprotective role of melatonin in neurological disorders |
title | The neuroprotective role of melatonin in neurological disorders |
title_full | The neuroprotective role of melatonin in neurological disorders |
title_fullStr | The neuroprotective role of melatonin in neurological disorders |
title_full_unstemmed | The neuroprotective role of melatonin in neurological disorders |
title_short | The neuroprotective role of melatonin in neurological disorders |
title_sort | neuroprotective role of melatonin in neurological disorders |
topic | Reviews |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6001545/ https://www.ncbi.nlm.nih.gov/pubmed/29498103 http://dx.doi.org/10.1002/jnr.24220 |
work_keys_str_mv | AT alghamdibs theneuroprotectiveroleofmelatonininneurologicaldisorders AT alghamdibs neuroprotectiveroleofmelatonininneurologicaldisorders |