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Epidural extension failure in obese women is comparable to that of non‐obese women

BACKGROUND: Management of labor epidurals in obese women is difficult and extension to surgical anesthesia is not always successful. Our previous retrospective pilot study found epidural extension was more likely to fail in obese women. This study used a prospective cohort to compare the failure rat...

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Autores principales: Eley, V. A., Chin, A., Tham, I., Poh, J., Aujla, P., Glasgow, E., Brown, H., Steele, K., Webb, L., van Zundert, A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6001550/
https://www.ncbi.nlm.nih.gov/pubmed/29399781
http://dx.doi.org/10.1111/aas.13085
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author Eley, V. A.
Chin, A.
Tham, I.
Poh, J.
Aujla, P.
Glasgow, E.
Brown, H.
Steele, K.
Webb, L.
van Zundert, A.
author_facet Eley, V. A.
Chin, A.
Tham, I.
Poh, J.
Aujla, P.
Glasgow, E.
Brown, H.
Steele, K.
Webb, L.
van Zundert, A.
author_sort Eley, V. A.
collection PubMed
description BACKGROUND: Management of labor epidurals in obese women is difficult and extension to surgical anesthesia is not always successful. Our previous retrospective pilot study found epidural extension was more likely to fail in obese women. This study used a prospective cohort to compare the failure rate of epidural extension in obese and non‐obese women and to identify risk factors for extension failure. METHODS: One hundred obese participants (Group O, body mass index ≥ 40 kg/m(2)) were prospectively identified and allocated two sequential controls (Group C, body mass index ≤ 30 kg/m(2)). All subjects utilized epidural labor analgesia and subsequently required anesthesia for cesarean section. The primary outcome measure was failure of the labor epidural to be used as the primary anesthetic technique. Risk factors for extension failure were identified using Chi‐squared and logistic regression. RESULTS: The odds ratio (OR) of extension failure was 1.69 in Group O (20% vs. 13%; 95% CI: 0.88–3.21, P = 0.11). Risk factors for failure in obese women included ineffective labor analgesia requiring anesthesiologist intervention, (OR 3.94, 95% CI: 1.16–13.45, P = 0.028) and BMI > 50 kg/m(2) (OR 3.42, 95% CI: 1.07–10.96, P = 0.038). CONCLUSION: The failure rate of epidural extension did not differ significantly between the groups. Further research is needed to determine the influence of body mass index > 50 kg/m(2) on epidural extension for cesarean section.
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spelling pubmed-60015502018-06-21 Epidural extension failure in obese women is comparable to that of non‐obese women Eley, V. A. Chin, A. Tham, I. Poh, J. Aujla, P. Glasgow, E. Brown, H. Steele, K. Webb, L. van Zundert, A. Acta Anaesthesiol Scand Regional Anaesthesia and Pain Therapy BACKGROUND: Management of labor epidurals in obese women is difficult and extension to surgical anesthesia is not always successful. Our previous retrospective pilot study found epidural extension was more likely to fail in obese women. This study used a prospective cohort to compare the failure rate of epidural extension in obese and non‐obese women and to identify risk factors for extension failure. METHODS: One hundred obese participants (Group O, body mass index ≥ 40 kg/m(2)) were prospectively identified and allocated two sequential controls (Group C, body mass index ≤ 30 kg/m(2)). All subjects utilized epidural labor analgesia and subsequently required anesthesia for cesarean section. The primary outcome measure was failure of the labor epidural to be used as the primary anesthetic technique. Risk factors for extension failure were identified using Chi‐squared and logistic regression. RESULTS: The odds ratio (OR) of extension failure was 1.69 in Group O (20% vs. 13%; 95% CI: 0.88–3.21, P = 0.11). Risk factors for failure in obese women included ineffective labor analgesia requiring anesthesiologist intervention, (OR 3.94, 95% CI: 1.16–13.45, P = 0.028) and BMI > 50 kg/m(2) (OR 3.42, 95% CI: 1.07–10.96, P = 0.038). CONCLUSION: The failure rate of epidural extension did not differ significantly between the groups. Further research is needed to determine the influence of body mass index > 50 kg/m(2) on epidural extension for cesarean section. John Wiley and Sons Inc. 2018-02-04 2018-07 /pmc/articles/PMC6001550/ /pubmed/29399781 http://dx.doi.org/10.1111/aas.13085 Text en © 2018 The Authors. Acta Anaesthesiologica Scandinavica published by John Wiley & Sons Ltd on behalf of Acta Anaesthesiologica Scandinavica Foundation This is an open access article under the terms of the http://creativecommons.org/licenses/by-nc/4.0/ License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited and is not used for commercial purposes.
spellingShingle Regional Anaesthesia and Pain Therapy
Eley, V. A.
Chin, A.
Tham, I.
Poh, J.
Aujla, P.
Glasgow, E.
Brown, H.
Steele, K.
Webb, L.
van Zundert, A.
Epidural extension failure in obese women is comparable to that of non‐obese women
title Epidural extension failure in obese women is comparable to that of non‐obese women
title_full Epidural extension failure in obese women is comparable to that of non‐obese women
title_fullStr Epidural extension failure in obese women is comparable to that of non‐obese women
title_full_unstemmed Epidural extension failure in obese women is comparable to that of non‐obese women
title_short Epidural extension failure in obese women is comparable to that of non‐obese women
title_sort epidural extension failure in obese women is comparable to that of non‐obese women
topic Regional Anaesthesia and Pain Therapy
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6001550/
https://www.ncbi.nlm.nih.gov/pubmed/29399781
http://dx.doi.org/10.1111/aas.13085
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