Brain metastases epidemiology in a Tunisian population: trends and outcome

AIM: We reported anatomo-clinical features of brain metastases (BMs) collected in a Tunisian medical oncology department. PATIENTS & METHODS: We retrospectively identified all cases of BM within a cohort of 7055 patients, treated for a histologically confirmed nonhematological cancer between 200...

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Autores principales: Benna, Mehdi, Mejri, Nesrine, Mabrouk, Manel, El Benna, Houda, Labidi, Soumaya, Daoud, Nouha, Boussen, Hamouda
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Future Medicine Ltd 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6001562/
https://www.ncbi.nlm.nih.gov/pubmed/29347839
http://dx.doi.org/10.2217/cns-2017-0020
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author Benna, Mehdi
Mejri, Nesrine
Mabrouk, Manel
El Benna, Houda
Labidi, Soumaya
Daoud, Nouha
Boussen, Hamouda
author_facet Benna, Mehdi
Mejri, Nesrine
Mabrouk, Manel
El Benna, Houda
Labidi, Soumaya
Daoud, Nouha
Boussen, Hamouda
author_sort Benna, Mehdi
collection PubMed
description AIM: We reported anatomo-clinical features of brain metastases (BMs) collected in a Tunisian medical oncology department. PATIENTS & METHODS: We retrospectively identified all cases of BM within a cohort of 7055 patients, treated for a histologically confirmed nonhematological cancer between 2000 and 2016. Data about age, sex and primary tumor were collected. RESULTS: Incidence was 1.9% and mean age was 54 years with a 1.24 sex ratio. BMs were symptomatic in 73.7% of cases after a median time of 16 months. A total of 73.4% patients receiving local therapy, 88% by whole brain radiation therapy and 21.6% had a metastasectomy. Lung and breast cancers were the primary in 80% of the BM. CONCLUSION: BM showed trends of young with underestimated incidence.
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spelling pubmed-60015622018-06-15 Brain metastases epidemiology in a Tunisian population: trends and outcome Benna, Mehdi Mejri, Nesrine Mabrouk, Manel El Benna, Houda Labidi, Soumaya Daoud, Nouha Boussen, Hamouda CNS Oncol Research Article AIM: We reported anatomo-clinical features of brain metastases (BMs) collected in a Tunisian medical oncology department. PATIENTS & METHODS: We retrospectively identified all cases of BM within a cohort of 7055 patients, treated for a histologically confirmed nonhematological cancer between 2000 and 2016. Data about age, sex and primary tumor were collected. RESULTS: Incidence was 1.9% and mean age was 54 years with a 1.24 sex ratio. BMs were symptomatic in 73.7% of cases after a median time of 16 months. A total of 73.4% patients receiving local therapy, 88% by whole brain radiation therapy and 21.6% had a metastasectomy. Lung and breast cancers were the primary in 80% of the BM. CONCLUSION: BM showed trends of young with underestimated incidence. Future Medicine Ltd 2018-01-19 /pmc/articles/PMC6001562/ /pubmed/29347839 http://dx.doi.org/10.2217/cns-2017-0020 Text en © 2018 Nesrine Mejri This work is licensed under a Creative Commons Attribution 4.0 License (http://creativecommons.org/licenses/by/4.0/)
spellingShingle Research Article
Benna, Mehdi
Mejri, Nesrine
Mabrouk, Manel
El Benna, Houda
Labidi, Soumaya
Daoud, Nouha
Boussen, Hamouda
Brain metastases epidemiology in a Tunisian population: trends and outcome
title Brain metastases epidemiology in a Tunisian population: trends and outcome
title_full Brain metastases epidemiology in a Tunisian population: trends and outcome
title_fullStr Brain metastases epidemiology in a Tunisian population: trends and outcome
title_full_unstemmed Brain metastases epidemiology in a Tunisian population: trends and outcome
title_short Brain metastases epidemiology in a Tunisian population: trends and outcome
title_sort brain metastases epidemiology in a tunisian population: trends and outcome
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6001562/
https://www.ncbi.nlm.nih.gov/pubmed/29347839
http://dx.doi.org/10.2217/cns-2017-0020
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