Cross‐Coupling of Sodium Sulfinates with Aryl, Heteroaryl, and Vinyl Halides by Nickel/Photoredox Dual Catalysis

An efficient photoredox/nickel catalyzed sulfonylation reaction of aryl, heteroaryl, and vinyl halides has been achieved for the first time. This newly developed sulfonylation protocol provides a versatile method for the synthesis of diverse aromatic sulfones at room temperature and shows excellent...

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Detalles Bibliográficos
Autores principales: Yue, Huifeng, Zhu, Chen, Rueping, Magnus
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Communications
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6001575/
https://www.ncbi.nlm.nih.gov/pubmed/29211330
http://dx.doi.org/10.1002/anie.201711104
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author Yue, Huifeng
Zhu, Chen
Rueping, Magnus
author_facet Yue, Huifeng
Zhu, Chen
Rueping, Magnus
author_sort Yue, Huifeng
collection PubMed
description An efficient photoredox/nickel catalyzed sulfonylation reaction of aryl, heteroaryl, and vinyl halides has been achieved for the first time. This newly developed sulfonylation protocol provides a versatile method for the synthesis of diverse aromatic sulfones at room temperature and shows excellent functional group tolerance. The electrophilic coupling partners are not limited to aryl, heteroaryl, and vinyl bromides and iodides, but also includes less reactive aryl chlorides as suitable substrates for this transformation.
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spelling pubmed-60015752018-06-21 Cross‐Coupling of Sodium Sulfinates with Aryl, Heteroaryl, and Vinyl Halides by Nickel/Photoredox Dual Catalysis Yue, Huifeng Zhu, Chen Rueping, Magnus Angew Chem Int Ed Engl Communications An efficient photoredox/nickel catalyzed sulfonylation reaction of aryl, heteroaryl, and vinyl halides has been achieved for the first time. This newly developed sulfonylation protocol provides a versatile method for the synthesis of diverse aromatic sulfones at room temperature and shows excellent functional group tolerance. The electrophilic coupling partners are not limited to aryl, heteroaryl, and vinyl bromides and iodides, but also includes less reactive aryl chlorides as suitable substrates for this transformation. John Wiley and Sons Inc. 2018-01-05 2018-01-26 /pmc/articles/PMC6001575/ /pubmed/29211330 http://dx.doi.org/10.1002/anie.201711104 Text en © 2018 The Authors. Published by Wiley-VCH Verlag GmbH & Co. KGaA. This is an open access article under the terms of the http://creativecommons.org/licenses/by-nc/4.0/ License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited and is not used for commercial purposes.
spellingShingle Communications
Yue, Huifeng
Zhu, Chen
Rueping, Magnus
Cross‐Coupling of Sodium Sulfinates with Aryl, Heteroaryl, and Vinyl Halides by Nickel/Photoredox Dual Catalysis
title Cross‐Coupling of Sodium Sulfinates with Aryl, Heteroaryl, and Vinyl Halides by Nickel/Photoredox Dual Catalysis
title_full Cross‐Coupling of Sodium Sulfinates with Aryl, Heteroaryl, and Vinyl Halides by Nickel/Photoredox Dual Catalysis
title_fullStr Cross‐Coupling of Sodium Sulfinates with Aryl, Heteroaryl, and Vinyl Halides by Nickel/Photoredox Dual Catalysis
title_full_unstemmed Cross‐Coupling of Sodium Sulfinates with Aryl, Heteroaryl, and Vinyl Halides by Nickel/Photoredox Dual Catalysis
title_short Cross‐Coupling of Sodium Sulfinates with Aryl, Heteroaryl, and Vinyl Halides by Nickel/Photoredox Dual Catalysis
title_sort cross‐coupling of sodium sulfinates with aryl, heteroaryl, and vinyl halides by nickel/photoredox dual catalysis
topic Communications
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6001575/
https://www.ncbi.nlm.nih.gov/pubmed/29211330
http://dx.doi.org/10.1002/anie.201711104
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AT zhuchen crosscouplingofsodiumsulfinateswitharylheteroarylandvinylhalidesbynickelphotoredoxdualcatalysis
AT ruepingmagnus crosscouplingofsodiumsulfinateswitharylheteroarylandvinylhalidesbynickelphotoredoxdualcatalysis

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