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Campath, calcineurin inhibitor reduction, and chronic allograft nephropathy (the 3C Study) – results of a randomized controlled clinical trial

Calcineurin inhibitors (CNIs, eg, tacrolimus) reduce short‐term kidney transplant failure, but chronic nephrotoxicity may contribute to late transplant loss. Elective conversion to inhibitors of the mammalian target of rapamycin (mTOR, eg, sirolimus) pathway might avoid long‐term CNI renal damage an...

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Detalles Bibliográficos
Autores principales: Haynes, Richard, Blackwell, Lisa, Staplin, Natalie, Herrington, William G., Emberson, Jonathan, Judge, Parminder K., Storey, Benjamin C., Landray, Martin J., Harden, Paul N., Baigent, Colin, Friend, Peter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6001618/
https://www.ncbi.nlm.nih.gov/pubmed/29226570
http://dx.doi.org/10.1111/ajt.14619

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