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Chlamydial virulence factor TarP mimics talin to disrupt the talin‐vinculin complex

Vinculin is a central component of mechanosensitive adhesive complexes that form between cells and the extracellular matrix. A myriad of infectious agents mimic vinculin binding sites (VBS), enabling them to hijack the adhesion machinery and facilitate cellular entry. Here, we report the structural...

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Detalles Bibliográficos
Autores principales: Whitewood, Austin J., Singh, Abhimanyu K., Brown, David G., Goult, Benjamin T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6001692/
https://www.ncbi.nlm.nih.gov/pubmed/29710402
http://dx.doi.org/10.1002/1873-3468.13074

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