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Chlamydial virulence factor TarP mimics talin to disrupt the talin‐vinculin complex
Vinculin is a central component of mechanosensitive adhesive complexes that form between cells and the extracellular matrix. A myriad of infectious agents mimic vinculin binding sites (VBS), enabling them to hijack the adhesion machinery and facilitate cellular entry. Here, we report the structural...
Autores principales: | Whitewood, Austin J., Singh, Abhimanyu K., Brown, David G., Goult, Benjamin T. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6001692/ https://www.ncbi.nlm.nih.gov/pubmed/29710402 http://dx.doi.org/10.1002/1873-3468.13074 |
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