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Vitamin D in patients with intellectual and developmental disability in secure in-patient services in the North of England, UK
AIMS AND METHOD: To assess the benefits of the introduction of routine vitamin D serum sampling for all patients admitted to a secure in-patient hospital in the North of England providing medium security, low security and rehabilitation services for offenders with intellectual and developmental disa...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cambridge University Press
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6001870/ https://www.ncbi.nlm.nih.gov/pubmed/29388522 http://dx.doi.org/10.1192/bjb.2017.8 |
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author | McKinnon, Iain Lewis, Thomas Mehta, Naomi Imrit, Shahed Thorp, Julie Ince, Chris |
author_facet | McKinnon, Iain Lewis, Thomas Mehta, Naomi Imrit, Shahed Thorp, Julie Ince, Chris |
author_sort | McKinnon, Iain |
collection | PubMed |
description | AIMS AND METHOD: To assess the benefits of the introduction of routine vitamin D serum sampling for all patients admitted to a secure in-patient hospital in the North of England providing medium security, low security and rehabilitation services for offenders with intellectual and developmental disability. The vitamin D levels of 100 patients were analysed at baseline. Those with insufficient or deficient levels were offered treatment and retested after 1 year. Vitamin D levels were analysed in the context of level of security, seasonality of test and co-prescription of psychotropic medications. RESULTS: Eighty-three per cent of patients had suboptimal vitamin D levels at initial test (41% deficient and 42% insufficient). This was seen among established patients and new admissions. Regression analysis of baseline vitamin D levels revealed no differences for levels of security, seasonality, whether patients were taking antipsychotic or anticonvulsant medication, or length of stay. Patients with deficiency or insufficiency were all offered supplementation. Those who opted in had significantly higher vitamin D levels at follow-up, compared with those who declined treatment. CLINICAL IMPLICATIONS: Established and newly admitted patients in our secure mental health services had substantial levels of vitamin D insufficiency. In the light of the morbidities that are associated with deficient vitamin D levels, routine screening and the offer of supplementation is advisable. DECLARATION OF INTEREST: None. |
format | Online Article Text |
id | pubmed-6001870 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2018 |
publisher | Cambridge University Press |
record_format | MEDLINE/PubMed |
spelling | pubmed-60018702018-06-15 Vitamin D in patients with intellectual and developmental disability in secure in-patient services in the North of England, UK McKinnon, Iain Lewis, Thomas Mehta, Naomi Imrit, Shahed Thorp, Julie Ince, Chris BJPsych Bull Original Papers AIMS AND METHOD: To assess the benefits of the introduction of routine vitamin D serum sampling for all patients admitted to a secure in-patient hospital in the North of England providing medium security, low security and rehabilitation services for offenders with intellectual and developmental disability. The vitamin D levels of 100 patients were analysed at baseline. Those with insufficient or deficient levels were offered treatment and retested after 1 year. Vitamin D levels were analysed in the context of level of security, seasonality of test and co-prescription of psychotropic medications. RESULTS: Eighty-three per cent of patients had suboptimal vitamin D levels at initial test (41% deficient and 42% insufficient). This was seen among established patients and new admissions. Regression analysis of baseline vitamin D levels revealed no differences for levels of security, seasonality, whether patients were taking antipsychotic or anticonvulsant medication, or length of stay. Patients with deficiency or insufficiency were all offered supplementation. Those who opted in had significantly higher vitamin D levels at follow-up, compared with those who declined treatment. CLINICAL IMPLICATIONS: Established and newly admitted patients in our secure mental health services had substantial levels of vitamin D insufficiency. In the light of the morbidities that are associated with deficient vitamin D levels, routine screening and the offer of supplementation is advisable. DECLARATION OF INTEREST: None. Cambridge University Press 2018-02 /pmc/articles/PMC6001870/ /pubmed/29388522 http://dx.doi.org/10.1192/bjb.2017.8 Text en © The Authors 2018 http://creativecommons.org/licenses/by/4.0/ This is an Open-Access article, distributed under the terms of the Creative Commons Attribution license (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted re-use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Original Papers McKinnon, Iain Lewis, Thomas Mehta, Naomi Imrit, Shahed Thorp, Julie Ince, Chris Vitamin D in patients with intellectual and developmental disability in secure in-patient services in the North of England, UK |
title | Vitamin D in patients with intellectual and developmental disability in secure in-patient services in the North of England, UK |
title_full | Vitamin D in patients with intellectual and developmental disability in secure in-patient services in the North of England, UK |
title_fullStr | Vitamin D in patients with intellectual and developmental disability in secure in-patient services in the North of England, UK |
title_full_unstemmed | Vitamin D in patients with intellectual and developmental disability in secure in-patient services in the North of England, UK |
title_short | Vitamin D in patients with intellectual and developmental disability in secure in-patient services in the North of England, UK |
title_sort | vitamin d in patients with intellectual and developmental disability in secure in-patient services in the north of england, uk |
topic | Original Papers |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6001870/ https://www.ncbi.nlm.nih.gov/pubmed/29388522 http://dx.doi.org/10.1192/bjb.2017.8 |
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