Phosphorylation of Beta-3 adrenergic receptor at serine 247 by ERK MAP kinase drives lipolysis in obese adipocytes

OBJECTIVE: The inappropriate release of free fatty acids from obese adipose tissue stores has detrimental effects on metabolism, but key molecular mechanisms controlling FFA release from adipocytes remain undefined. Although obesity promotes systemic inflammation, we find activation of the inflammat...

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Detalles Bibliográficos
Autores principales: Hong, Shangyu, Song, Wei, Zushin, Peter-James H., Liu, Bingyang, Jedrychowski, Mark P., Mina, Amir I., Deng, Zhaoming, Cabarkapa, Dimitrije, Hall, Jessica A., Palmer, Colin J., Aliakbarian, Hassan, Szpyt, John, Gygi, Steven P., Tavakkoli, Ali, Lynch, Lydia, Perrimon, Norbert, Banks, Alexander S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2018
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6001906/
https://www.ncbi.nlm.nih.gov/pubmed/29661693
http://dx.doi.org/10.1016/j.molmet.2018.03.012

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