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Evaluation of amnion-derived mesenchymal stem cells for treatment-resistant moderate Crohn’s disease: study protocol for a phase I/II, dual-centre, open-label, uncontrolled, dose–response trial
INTRODUCTION: The medical treatment options for patients with Crohn’s disease (CD) are limited and patients resistant to those therapies are left requiring surgical operations that usually only achieve some symptomatic relief. Mesenchymal stem cells (MSC) have been shown to be effective for the trea...
Autores principales: | Otagiri, Shinsuke, Ohnishi, Shunsuke, Miura, Arisa, Hayashi, Hiroshi, Kumagai, Izumi, Ito, Yoichi M, Katsurada, Takehiko, Nakamura, Shiro, Okamoto, Rika, Yamahara, Kenichi, Cho, Kyu Yong, Isoe, Toshiyuki, Sato, Norihiro, Sakamoto, Naoya |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BMJ Publishing Group
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6001910/ https://www.ncbi.nlm.nih.gov/pubmed/29915666 http://dx.doi.org/10.1136/bmjgast-2018-000206 |
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