Cargando…

The role of genetic variation of human metabolism for BMI, mental traits and mental disorders

OBJECTIVE: The aim was to assess whether loci associated with metabolic traits also have a significant role in BMI and mental traits/disorders METHODS: We first assessed the number of single nucleotide polymorphisms (SNPs) with genome-wide significance for human metabolism (NHGRI-EBI Catalog). These...

Descripción completa

Detalles Bibliográficos
Autores principales:	Hebebrand, Johannes, Peters, Triinu, Schijven, Dick, Hebebrand, Moritz, Grasemann, Corinna, Winkler, Thomas W., Heid, Iris M., Antel, Jochen, Föcker, Manuel, Tegeler, Lisa, Brauner, Lena, Adan, Roger A.H., Luykx, Jurjen J., Correll, Christoph U., König, Inke R., Hinney, Anke, Libuda, Lars
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2018
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6001916/ https://www.ncbi.nlm.nih.gov/pubmed/29673576 http://dx.doi.org/10.1016/j.molmet.2018.03.015

Ejemplares similares

The Role of Genetic Variation of BMI, Body Composition, and Fat Distribution for Mental Traits and Disorders: A Look-Up and Mendelian Randomization Study
por: Peters, Triinu, et al.
Publicado: (2020)

Effect of an vitamin D deficiency on depressive symptoms in child and adolescent psychiatric patients – a randomized controlled trial: study protocol
por: Föcker, Manuel, et al.
Publicado: (2018)

Assessing causal links between metabolic traits, inflammation and schizophrenia: a univariable and multivariable, bidirectional Mendelian-randomization study
por: Lin, Bochao D, et al.
Publicado: (2019)

Vitamin D and the Risk of Depression: A Causal Relationship? Findings from a Mendelian Randomization Study
por: Libuda, Lars, et al.
Publicado: (2019)

A mendelian randomization study on causal effects of 25(OH)vitamin D levels on attention deficit/hyperactivity disorder
por: Libuda, Lars, et al.
Publicado: (2020)

Lack of Evidence for a Relationship Between the Hypothalamus-Pituitary-Adrenal and the Hypothalamus-Pituitary-Thyroid Axis in Adolescent Depression
por: Hirtz, Raphael, et al.
Publicado: (2021)

Suggestive Evidence for Causal Effect of Leptin Levels on Risk for Anorexia Nervosa: Results of a Mendelian Randomization Study
por: Peters, Triinu, et al.
Publicado: (2021)

Size Matters: The CAG Repeat Length of the Androgen Receptor Gene, Testosterone, and Male Adolescent Depression Severity
por: Hirtz, Raphael, et al.
Publicado: (2021)

Causal Effect of Age at Menarche on the Risk for Depression: Results From a Two-Sample Multivariable Mendelian Randomization Study
por: Hirtz, Raphael, et al.
Publicado: (2022)

Effect of vitamin D deficiency on depressive symptoms in child and adolescent psychiatric patients: results of a randomized controlled trial
por: Libuda, Lars, et al.
Publicado: (2020)

Evaluation of Metabolic Profiles of Patients with Anorexia Nervosa at Inpatient Admission, Short- and Long-Term Weight Regain—Descriptive and Pattern Analysis
por: Föcker, Manuel, et al.
Publicado: (2020)

The adrenal steroid profile in adolescent depression: a valuable bio-readout?
por: Hirtz, Raphael, et al.
Publicado: (2022)

Evidence for correlations between BMI-associated SNPs and circRNAs
por: Rajcsanyi, Luisa Sophie, et al.
Publicado: (2022)

PTBP2 – a gene with relevance for both Anorexia nervosa and body weight regulation
por: Zheng, Yiran, et al.
Publicado: (2022)

Evaluation of the MC3R gene pertaining to body weight and height regulation and puberty development
por: Zheng, Yiran, et al.
Publicado: (2023)

Eating disorders: the current status of molecular genetic research
por: Scherag, Susann, et al.
Publicado: (2009)

Low 25(OH)-vitamin D concentrations are associated with emotional and behavioral problems in German children and adolescents
por: Husmann, Christiane, et al.
Publicado: (2017)

Rapid amelioration of anorexia nervosa in a male adolescent during metreleptin treatment including recovery from hypogonadotropic hypogonadism
por: Antel, Jochen, et al.
Publicado: (2021)

From monogenic to polygenic obesity: recent advances
por: Hinney, Anke, et al.
Publicado: (2010)

Vitamin D Level Trajectories of Adolescent Patients with Anorexia Nervosa at Inpatient Admission, during Treatment, and at One Year Follow Up: Association with Depressive Symptoms
por: Föcker, Manuel, et al.
Publicado: (2021)

Dietary Acid Load and Mental Health Outcomes in Children and Adolescents: Results from the GINIplus and LISA Birth Cohort Studies
por: Bühlmeier, Judith, et al.
Publicado: (2018)

No Effect of Thyroid Dysfunction and Autoimmunity on Health-Related Quality of Life and Mental Health in Children and Adolescents: Results From a Nationwide Cross-Sectional Study
por: Hirtz, Raphael, et al.
Publicado: (2020)

Short-term metreleptin treatment of patients with anorexia nervosa: rapid on-set of beneficial cognitive, emotional, and behavioral effects
por: Milos, Gabriella, et al.
Publicado: (2020)

Melanocortin-4 Receptor and Lipocalin 2 Gene Variants in Spanish Children with Abdominal Obesity: Effects on BMI-SDS after a Lifestyle Intervention
por: Morell-Azanza, Lydia, et al.
Publicado: (2019)

Successful Treatment with Atomoxetine of an Adolescent Boy with Attention Deficit/Hyperactivity Disorder, Extreme Obesity, and Reduced Melanocortin 4 Receptor Function
por: Pott, Wilfried, et al.
Publicado: (2013)

Suggestive Evidence for an Antidepressant Effect of Metreleptin Treatment in Patients with Lipodystrophy
por: Vieira, Diana Branco, et al.
Publicado: (2022)

Val103Ile polymorphism of the melanocortin-4 receptor gene (MC4R) in cancer cachexia
por: Knoll, Susanne, et al.
Publicado: (2008)

Placebo response rates and potential modifiers in double-blind randomized controlled trials of second and newer generation antidepressants for major depressive disorder in children and adolescents: a systematic review and meta-regression analysis
por: Meister, Ramona, et al.
Publicado: (2018)

Relevance of polymorphisms in MC4R and BDNF in short normal stature
por: Herrfurth, Nikolas, et al.
Publicado: (2018)

Prevalence estimates of putatively pathogenic leptin variants in the gnomAD database
por: Rajcsanyi, Luisa Sophie, et al.
Publicado: (2022)

Clinical Trials Required to Assess Potential Benefits and Side Effects of Treatment of Patients With Anorexia Nervosa With Recombinant Human Leptin
por: Hebebrand, Johannes, et al.
Publicado: (2019)

The involvement of the canonical Wnt‐signaling receptor LRP5 and LRP6 gene variants with ADHD and sexual dimorphism: Association study and meta‐analysis
por: Grünblatt, Edna, et al.
Publicado: (2018)

Analysis of sequence variations in the suppressor of cytokine signaling (SOCS)-3 gene in extremely obese children and adolescents
por: Hölter, Katja, et al.
Publicado: (2007)

Alterations in B cell subsets correlate with body composition parameters in female adolescents with anorexia nervosa
por: Freff, Jana, et al.
Publicado: (2021)

Novel common copy number variation for early onset extreme obesity on chromosome 11q11 identified by a genome-wide analysis
por: Jarick, Ivonne, et al.
Publicado: (2011)

Increased constraints on MC4R during primate and human evolution
por: Hughes, David A., et al.
Publicado: (2008)

Indications for Potential Parent-of-Origin Effects within the FTO Gene
por: Liu, Xuanshi, et al.
Publicado: (2015)

Non-replication of an association of CTNNBL1 polymorphisms and obesity in a population of Central European ancestry
por: Vogel, Carla IG, et al.
Publicado: (2009)

Expression of CXCR4 on CD4(+) T cells predicts body composition parameters in female adolescents with anorexia nervosa
por: Freff, Jana, et al.
Publicado: (2022)

Lipocalin 2 – mutation screen and serum levels in patients with anorexia nervosa or obesity and in lean individuals
por: Zheng, Yiran, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_v6hog979i1d5ekh5io26iqa9fc