mTORC1-dependent increase in oxidative metabolism in POMC neurons regulates food intake and action of leptin

OBJECTIVE: Nutrient availability modulates reactive oxygen species (ROS) production in the hypothalamus. In turn, ROS regulate hypothalamic neuronal activity and feeding behavior. The mechanistic target of rapamycin complex 1 (mTORC1) pathway is an important cellular integrator of the action of nutr...

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Detalles Bibliográficos
Autores principales: Haissaguerre, Magalie, Ferrière, Amandine, Simon, Vincent, Saucisse, Nicolas, Dupuy, Nathalie, André, Caroline, Clark, Samantha, Guzman-Quevedo, Omar, Tabarin, Antoine, Cota, Daniela
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2018
Materias:
Brief Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6001919/
https://www.ncbi.nlm.nih.gov/pubmed/29699927
http://dx.doi.org/10.1016/j.molmet.2018.04.002

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6001919/
https://www.ncbi.nlm.nih.gov/pubmed/29699927
http://dx.doi.org/10.1016/j.molmet.2018.04.002

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