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Profiling of G protein-coupled receptors in vagal afferents reveals novel gut-to-brain sensing mechanisms
OBJECTIVES: G protein-coupled receptors (GPCRs) act as transmembrane molecular sensors of neurotransmitters, hormones, nutrients, and metabolites. Because unmyelinated vagal afferents richly innervate the gastrointestinal mucosa, gut-derived molecules may directly modulate the activity of vagal affe...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6001940/ https://www.ncbi.nlm.nih.gov/pubmed/29673577 http://dx.doi.org/10.1016/j.molmet.2018.03.016 |