Profiling of G protein-coupled receptors in vagal afferents reveals novel gut-to-brain sensing mechanisms

OBJECTIVES: G protein-coupled receptors (GPCRs) act as transmembrane molecular sensors of neurotransmitters, hormones, nutrients, and metabolites. Because unmyelinated vagal afferents richly innervate the gastrointestinal mucosa, gut-derived molecules may directly modulate the activity of vagal affe...

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Detalles Bibliográficos
Autores principales: Egerod, Kristoffer L., Petersen, Natalia, Timshel, Pascal N., Rekling, Jens C., Wang, Yibing, Liu, Qinghua, Schwartz, Thue W., Gautron, Laurent
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2018
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6001940/
https://www.ncbi.nlm.nih.gov/pubmed/29673577
http://dx.doi.org/10.1016/j.molmet.2018.03.016

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